My Dr. gradually tapered my dose, but the side effects are horrible. I am having dizziness, mind zaps, chills, emotional craziness & just real tired of feeling like this. I took my last dose 5 days ago. How much longer will this last?
How long do withdrawals from Prestiq last?
Question posted by angbob on 15 Jan 2012
Last updated on 22 February 2021
The information on this page reflects personal experiences shared by our community members. It is not reviewed for medical accuracy and should not replace professional medical advice.
42 Answers Page 3
I am currently weaning off Pristiq 100. My Dr had me cut my 100s in half and take 1 (50 mg) every day for 2 weeks and then take that half pill every other day for 2 weeks. Wow. I am on the 1st week of every other day and today was the first day I really had a rough time with it. Symptoms include: headache, tiredness, stomach pain, nausea, shaky, crying, cold chills, then hot feelings, dizziness, mind zaps, and overall anxiety. I can't wait for this drug to be out of my system. Good luck to all of you who are in the same boat.
I have been on Pristiq for 3 years. I was on 100 then went to the 50's about 3-4 months ago and then cut those in half about a month ago. I am on day 7 of taking the "25's" every other day and I am suffering. I wasn't too bad the first couple of days but now I have vertigo (brain zaps), nausea, headaches, my core temp feels super hot, and nothing I do makes me feel any better. This is my second attempt at cutting this drug out of my system. How long did it take for you in the end?
Does anyone here have a successful story coming out the other end? My doctor suggested extending the hours between taking the drug. So day 1 I take it in the morning day 2 I take it afternoon day 3 very late at night day 4 I don't take it at all then I start back at day 1 cycle again. Im not experiencing any brain zaps which I have in the past and I don't wish them on my worst enemy. Today I had uncontrollable crying a fever and aches. Is it worth pushing through? Or should I succumb to just taking a pill everyday for the rest of my life?
I am doing much better since my original post. I am down to last 2 (half) pills that have been spaced every 2 nights for 3 weeks. I encourage you to try to stick with weaning yourself. The longer you are on the drug the worse the withdrawls later if you have to stop taking it for some reason. I have taken my time weaning because right before my insurance quit covering the drug, I had placed a mail order and received a 90 day supply so I had plenty. My dr wanted me to do the half pill (50 mg) every 2 nights for 2 weeks. I have done almost a month. I hope I do ok once I take that last pill. Fingers crossed. Good luck to you!!
I'm just wondering, did your doctor say you could take HALF of the the 50 mg pill? I thought that wasn't possible because the 50mg shouldn't be split... something to do with the time release of the medication being affected(?) I want to start tapering down from 50mg if at all possible.
Hey pam it seems doctors have no clue when it comes to that. I split mine for a couple weeks by doctors orders and the random bursts of depression tears and anxiety were hard to deal with. I didn't enjoy it at all. It's like dumping a whole lot into your system at once. Instead of gradually. Good job on doing your own research.
I've been on PRISTIQ for 4 years. In the last 8 months of body aches I decided to ween myself off this drug. I spoke to my Doc about it and he wasn't very helpful other than saying cut back slowly if you decide to get off. I am on my 3rd day of cutting my 50mg in half. I feel crazy, dizzy, heavy chest, tired, brain fog, heart racing, restless sleep... I cannot believe they prescribe this drug! I will never put this in my system again and can't wait till I'm totally past this. My plan is to take it slow and cut back slowly even if it takes months... I just don't want to have to keep taking this the rest of my life.
It has been 9 days for me. I'm a mess, still dealing with dizziness, brain zaps, crying, nausea, exaustion and anxiety. I am so tierd of this... will I ever get through this?
I like Kitrys weaning process. I have been on Pristiq for nearly 10 years and really want to come off it. I suffer anxiety, not depression and had managed my whole life with valium. When my anxiety flared up, I'd take valium for a few days and 'reset' my system and I'd be fine for months. But, doctors don't like to prescribe valium and when I moved cities I could not find one that would. So I tried everything from Effexor to Zoloft. All were disasters. I found Pristiq and was finally feeling well. I can't see how Drs can think 365 Pristiq a year is better than 20-30 valium! Anyhow, I'm trying to wean off again. I've tried compounding half tablets into slow release capsules but that didn't work. I'll try your method of spacing doses. I have now found a Dr that will give me valium for anxiety. I did not suffer depression.
Good luck to all of us.
I have figured out the best way with very minimal withdrawal symptoms.
I took 50mg every morning for almost 3 years. I was prescribed the drug by my old doctor for anxiety. It definitely worked however I found I was almost a zombie with no emotional attachment to anything. I even split with my wife of 14 years while taking this evil drug.
Let me explain how I was able to get off of it
I spaced the time between pills each day by adding 1 hour extra to each day. As these pills are “time released” and you can’t split them I figured I would split the time instead of the pill
Day 1 - take pill at 8am
Day 2- 25 hours between pill 9am
Day 3- 26 hours between pill 11am
Day 4- 27 hours between pill 2pm
Day 5- 28 hours between pill 6pm
Day 6- 29 hours between pill 11pm
Day 7- 30 hours between pill 5am
To simplify this and keep track I have downloaded the Timer+ app for iPhone. Works like a charm and reminds me (no matter what time of day or night) when to take the next pill.
My plan is to get to about 4 or 5 days between pills and then just stop taking them
I have tried 4 times before to get off these pills and this method finally seems to work.
I've been on Pristiq for the past 2 years (50mg, then 100mg, and 50mg again), and I've gone cold turkey. My dr. says it's not a drug that you're supposed to taper off, neither break the pill or take on alternating days. I had really bad side effects, like excessive night sweat, anorgasmy, loss of libido, mind confusion, nistagm (shaky eyes) and other symptoms.
The treatment was great. I was a little bit distant and less emotional, but on different occasions, when I didn't take the pill in the morning, I'd feel severe side effects.
Cold turkey was going fine, maybe because I didn't forget the pill, so my mind was at ease without the meds. On my sixth day (yesterday) without it, around 5pm, I had a real bad loss of balance, my head was spinning, and a little nausea. It felt like I was high on something else. Had a little trouble to sleep, but I blacked out early and had, again, one of those surreal-extra-real-dreams. In the next morning I was still dizzy, so I took dramamine and the dizziness and drowsiness are under control.
Always remember that every drug acts differently on each person. Side effects and withdrawal will vary. DO NOT interrupt treatment without your dr's approval, and DO NOT take the drug without professional help - if you do, you're only half-helping yourself. :)
I don't know that's what I want to know.. I am having terrible withdrawal symptoms.. Crying, very bad night sweats, teeth chattering,headaches, stomach pain, heart racing before and in the midst of waking up from a restless night, and the feeling of coming to a stop on an elevator.. I guess that's the brain zaps everyone is calling it.. Im too looking for help, I am having the worse time of my life because of this med.. I will be so happy when its completely out of my system. I started taking it two weeks ago and stopped because my insurance won't pay for it, it has now been two full days since I quit
can I ask how you are doing? it's day 2 and I feel absolutely horrible! Shaking, crying, mind zaps, headache. My dose, 100mg was on it for 3 yrs
I have a question ... I've been tampering off pristiq now for a week taking it every other day . It's awful ... Feel like I have a bad hangover... Does the withdrawals get worse when I have have to start missing two days in a roll ??? Praying this will be over soon !!! Please help with advise . Thanks
How are u feeling ??? Better ?
I haven't been the same since, I started having seizures.. Very vivid dreams, almost real like. As of right now as I relax I feel ok. But like I said I haven't been the same since
Did your dr taper you off or did you just quit? I have tried to just quit and was told it's a big no no. I had the same symptoms as you lashon 123. I was told you have to be tapered off to lessen some of the effects. Hope this helps.
I don't have a complete answer yet. I started taking the Prestiq (50 mg) two years ago. My doctor prescribed it to give me energy for my Fibromyalgia. I could kick myself in the head for not checking it out. Last summer I started having very bad dizziness, ringing in my ears and nausea. I was sick for almost three months before being diagnosed with Meniere's Disease. I forgot to get the script filled on time in December 2014. It took my doctor three days to get the script to my pharmacy and by then the Meniere's had started. I went to my family doctor and we decided to wean me off the medication. The Meniere's got worse so I had to call my ENT and he had to precribe valium for three days to settle down the dizziness, nausea, and ringing in my ears. It worked. I took the last dose on January 3rd. I have been drinking lots of water with lemon in it to try to keep flushing my body.
As of today, January 15th I still have ringing in my ears and the brain zaps that I got when the Meniere's started are still happening. I am going to report all of this to the FDA. I will never take this or any kind of drug like it again. Not only has it caused another disease, but I may never get over the Meniere's because of the Prestiq.
This is very scary to me. The idea that from taking one drug you can develop a another illness. Thanks for sharing. Good idea to report this to the FDA. I'm know I'll get off the drug some way, and I figure it will take a long time. Regardless, I'll be off eventually. It takes lots of will power, persistence, and help from people in this community.
What do I do I am on 150mg. of pristique for at least three years for depression. I cut back to100 tonight .How should I do this??
I am very sorry to hear of all that happened to you while taking Pristiq. My psychiatrist, who is young, recommended that I begin Pristiq while tapering off Abilify - another doozy to wean since I was exposed to it for over 10 years. So when I read about all the problems people were having with withdrawal from Pristiq (Brain zaps and dizziness and your Meniere's), I knew what a mistake it would have been. Thank god for drugs.com's support groups allowing me to see these drug for what they are worth. Plus, if any of you readers have an opinion on the atypical antipsychotics for anxiety reduction and a mood disorder, please take a look at the Abilify thread. There are more and more antipsychotics on the market these days disguised as the answer for depression, bipolar, hallucinations and delusions. Always come here first to verify what a doctor wants to prescribe.
I've been on Pristiq 100mg for 3 years. I was diagnosed with major depression, anxiety and bulimia. Personally, I didn't notice much of a difference while taking it. But when I missed a dose by a day I'd feel extremely hungover and couldn't concentrate. My psychiatrist said something that I took really personally and just didn't want to go back to him, so he stopped prescribing me pristiq. I realized I couldn't get anymore refills with about 3 tablets left. So I cut them in half and took the halves every other day and then cut them in fourths. This was hell, especially during my final week of college. I'd hear my name being called a few times (slight auditory and visual hallucinations...
Extremely freaky) My significant other almost broke up because Of my crazy mood swings, I was having brain zaps all the time, cried at basically anything and everything, binged on so much 'junk food,' and probably gained about ten pounds. Also a few days ago I went out to a restaurant and fainted/passed and wet my pants in the process, it was probably because I was dehydrated but it was extremely scary.. Because I wasn't sure if it tied in with being off of pristiq. I've been off completely for about a week now. I feel a lot better than before, I still get occasional brainZaps, am tired often and am drinking a ton of water. Also I notice I get chills where it feels like my toenails and fingernails are going to fall off.. It feels like my sensory nerves are a little off at times. This is the absolute worse drug to get off of.
I'm so thankful for this support group. I'd like to hear anyone's opinions or related stories... Stick in there everyone.
I just wanted to add that I am having brain zaps, I call them Sparkelys, now for 4 years after stopping Pristiq. I can't work anymore they are such a distraction. I was a Sr Business Analyst in Information Technology and concentrating became impossible.
this is very late I'm sure you probably won't even see it I went from a hundred milligrams Pristiq I just jumped off 25 mg today I hope I withdrawal isn't too bad I'm not feeling too bad right now but I was pretty sick during the wea process but I am so sorry to hear that you can't even work anymore this drug is poison I hope you sued the company or Pfizer!
I know this post is old, however, I hope someone like me who was searching for answers finds this post helpful. I was on Prestiq for four years and have just started tapering off of the drug. I have experienced withdrawals but after a couple of weeks I have found myself drug free and getting stronger! I have found that I like myself and my life so much better without the use of this drug. First and foremost I have used the power of prayer! I do not have the strength to overcome these symptoms alone, but through prayer for each new day, I am overcoming and getting stronger one day at a time. Secondly, eat clean!! Junk creates brain fog and I am learning the power of food. Let me recommend Rick Warren's book "The Daniel Plan" to help get started.
Third, Exercise! I have found that this helps me get each day started! Leslie Sansone's DVD "Walk Strong" can be found at WalMart and is a very doable program that helps to get you moving! I know this sounds simple but with 1) Prayer 2) Proper Diet and 3) Exercise , I am gaining my life back one day at a time! Praise God!
I'm late on this conversation by a few years lol. I have begun my detox process. I have been on pristiq for about 4 years now. I never made the withdrawal connection until recently. I had missed doses in the past, but because the effects have always happened on the following days I didn't put it together. I had attributed what was going on to pre menopausal stuff. Today I missed my 100mg dose yesterday because I was waiting to get a 50mg scrip. Today I took the 50mg. I have been dizzy all day and my brain zaps, which are more like a rhythmic buzz has been persistent. I am so glad that people have shared stories.
I am so thankful to have found this forum. I have been on the top dose of Pristiq (100mg) for 4 and 1/2 years. My insurance changed so I'm paying out of pocket. I recently became connected with God and prayed to help me be able to stop this medicine bc of the cost and the fact that it doesn't really do anything positive. I was diagnosed 8 years ago with anorexia, anxiety and depression. I am on my 4th day without the medicine and noticed I feel more alive. The first couple days weren't horrible. I experienced blurred vision, dizziness, almost vertigo type symptoms. The mind zaps are there too hit get less severe each day. The night sweats are bad as well as the chills on the 4th day. But my biggest concern re the night terrors I'm having. I'm now afraid to sleep. I keep praying for strength and also know that it is the drug withdrawal. I felt more unhappy and moody on the medicine. I laugh more and feel energized without it.
I just want to make it through the 7 days when my pharmacist said t will be completely out of my system. Does anyone have helpful suggestions for peaceful sleep?
Thank you. This is so difficult. Day 3 and it's a holiday.
Old thread but same drug with same discontinuance problems, from what the thread reads. After 5 years using Effexor XR, the Pfizer precursor of Pristiq, the effects of cessation were intense from the first day. Brain shivers and all that. Now, after 7 years using Pristiq, shut it down three days ago after three weeks at 50 mg every other day. Same symptoms, not as intense. Knowing the Effexor eventually stopped its antics really helps in coping with the Pristiq. And, as many have said, the power of prayer can carry the day. Also found that a psychiatrist is far better at evaluating this type of drug than the average GP. Really helped to see there are alternatives beyond medication.
I'd like to add that drinking a natural tea such as chamomile is good. Many people complain that it tastes horrible, and I thought the same. Some people suggest adding honey etc. to make it more palatable. For me, just to look at the box makes me want to gag. I started to drink it again. Now I am able to drink the tea without anything in it. As it is very hot where I live, I make the tea in advance, refrigerate it, and sip it cold.
I'm currently on day 7 of weaning off Pristiq. I took 50mg for 4 years. The side effects of withdrawal are just as you described. I'm a Believer, currently doing a sugar detox & praying this all ends soon. How did things work out for you?
Hello Christie, What was the reason why you decided to get off of Prestiq? Ive been on it for a few months after a terrible break up, the antidepressant Cymbalta didnt work any more. My doctor put me on 100mgs of Prestiq, I feel ok on them, no bad side effects that I could see.. however I ran out this week and forgot to get it refilled and it's been day 3 now without it and I feel terrible. Very emotional and unstable. I'm constantly dizzy and tired too. I can't sleep at night though. Being off this medication wasn't on purpose but now that I'm reading all of these things on side effects. I'm a bit concerned. I'm just wondering if you experienced any side effect while you were on the medication. I'm also a believer in the power of prayer. I know that God is the one keeping me alive during these tough times in my life.
Hi there everyone like u all I was searching for an easy answer to tapering off this drug. I eat clean, don't drink, do yoga, meditate, etc but 100 ml of this drug (albeit gave me some clarity to deal with life) is destroying me slowly!! I wake up with hives every morning in sweaty areas then have to take antihistamines to counteract the side effects of pristiq!! I don't have my creative side anymore and love drawing! I hate chemicals and avoid all parabens etc in hair body and makeup!! Why do I need this stuff! Ok I was suisidal and shrink had to give me something!! But now I want to try and come off!! Listen to don tolman pod cast re pharmaceutical drugs!! I was diagnosed with many mood disorders one being hypersensitivity so I struggle when coming down drugs!!
Thank you so much for sharing this. I’m on day 4 of no longer taking Pristiq, and I can’t even begin to describe the hell I feel. Irritable, angry, dizzy, non stop weeping, and awful brain zaps. I feel hopeless. I keep trying to tell myself that it will get better, but these past two days have been extra extra hard. It’s hard to focus at work. I just constantly cry. I just want to see the light at the end of the tunnel. Reading this post has helped. It’s encouraging, and gives me a little hope that this will pass, and I will feel better soon!
1 day 8 hours ago
I have been on Pristiq since June 2012 50mgs daily. I'm on day 4 of quitting cold turkey. First two days I didn't feel any different unti day 3 and 4. Been getting brain zaps all day. They are not to bothersome just don't move your eyes or head around to quick. I did puke yesterday, only because I exercised. Maybe I shouldn't have. I thought the withdrawals would be worse but they are not, thank god. I didn't want to taper off because I felt I would be prolonging the withdrawal symptoms. I didn't want to take a pill for the rest of my life so I quit. My wife says I've changed and that I was distant and wanted me back. I actually got worse when I started taking the pills. I had many anxiety attacks the first three weeks while on it. Oh I forgot to mention, I was on Pristiq for anxiety only not depression. I hope my side of the story about Pristiq helps. Any questions, feel free to ask away.
I have been on Pristiq for General anxiety disorder and mild depression for several years. I have been apathetic since I have been on it and want to start feeling emotions again. I am on day 6 and it hasn't been to bad as long as I am aware that the dizziness and brain zaps are from withdrawals. I didn't feel any effects for the first 2-3 days and then I had a headache, dizziness and brain zaps. Each day it gets a little better. I agree with another poster just don't move your head to fast a nod when the dizziness and brain zaps occur they are short lived and I find it easy to tolerate to close my eyes for a minute.
It's not a nasty drug and I've experienced similar withdrawal symptoms with other anti depressants.
I have been very tired as well.
Thank you for writing about your experience. It helped me a lot
It’s a total train wreck trying to rid yourself of this drug. Excessive crying, headaches, nausea, sweats. It’s been over a month since I’ve last taken this drug, and I feel hopeless. Didn’t help me at all with my anxiety.
It will take time. I have been going through the very long withdrawal process over the past 2 months, have been completely off the nasty drug for 23 days, and am STILL having slight withdrawal symptoms (dizzy, mind zaps, headache). I am hoping that they will end soon as I am now on an actual detox program to get rid of the drug. HORRIBLE DRUG with HORRIBLE WITHDRAWAL symptoms... would have been nice to know when I first started taking it. Good luck - look to friends and family for support - take vitamins and eat as healthy as you can. When you think you may be going "crazy"... try not to panic, take a deep breath and know that it's the drug and not you.
I am so glad to find someone with this very helpful info on pristiq withdrawal as I just started the tapering process and already feel absolutely horrible this med is terrible also like u said I also wasn't told any of this when I started taking it I have nausea,headache,fatigue,and horrible skock like feeling in my head like I'm being zapped with electricity so thanks for posting it helps a lot so ik what to expect.
I've been completely off pristiq for about five days and still very dizzy. Headaches have stopped, still have sweats at night but they have stopped during the day today only. The dizziness is so extreem I can't do any housework, work or anything really.
My doc put me on Prestiq because of a little anxiety and hot flashes... well I went on vaca forgot my rx... it was horrible, nite sweats,dizziness,nauseous, actually threw up, vertigo, headaches and brain zaps,also I could not sleep... I want to wean myself off this and would like any suggestions.I would rather take zanex... I could take it only when needed and never had any side affects... These so called anti anxiety depression drugs are worse than anything I have ever taken because your body is hooked and you go through the worse symptoms and withdrawals to get off !!! So if any one knows haow I can get off of this I would appreciate your help !!!
What is your detox because I can not handle this mind zapping and joint pains. When does it stop???
I have been on 50 mg pristig for alittle over two years decided I didn't want to take it anymore I started missing every other day for a couple of weeks feell really really tired I have real bad dizzy spells have been taking Bonnie and it helps some have had nausea a lot also especially if I drink coffee. Last week I started skipping 3 days it has gotten alittle better but still dizzy tired and have nausea I'm thinking of just trying to stop altogether tomorrow but don't know how bad it might get
This is my 5th day off pristiq. Man! Brain zaps are so strong every time I move my head. I don't think I can exercise. I can't go out. I'm tired and just feel miserable. I am drinking lots of water. Trying to help flush out the toxins faster. I am now on fetzima. Fingers crossed. I hope the withdrawals don't last months. There goes my summer! Never had this problem with other antidepressants. Wicked stuff.
I've on pristiq + faverine for about 18 months but i stopped taking faverine 4 months ago and showed no major side effects i decided myself to also stop taking pristiq 5 days ago and no side effects at all thks god ... i know its wrong and should have consulted my doctor ... but this illness can not be cured unless you convince urself that u can beat it needs a strong will i guess
Interesting comments.
I started on 50mg Pristiq MR in July last year, and was increased to 100mg in February this year. However, about five days ago now I ran out and couldn't get in to see my doctor until next week (poor time management on my part). It's almost as interesting as it is inconvenient. I did miss taking my meds for a few days once when I was on the 50mg dosage, and on the third day was feeling like I wanted to vomit, and also a little dizziness, however this time there is no nausea at all, just some dizziness and the increasingly frequent 'mind zap' sensation that some people have mentioned. I had been planning to ask my doctor about coming off it anyway, so hopefully he has some advice for me (probably in the form of a lecture), which I will share here if memory serves.
I suggest you contact your doctor and let him know. He can change your dose to fit your needs. However you must let him know !
Unfortunately it could last another week or so, but since it has already been almost a week the withdrawal effects should gradually lessen. If it really is unbearable you could try the lowest dose of Pristiq and take it every other day for a couple of weeks, then every third day for a couple of weeks before stopping again.
The bad physical withdrawals should be starting to get better by day five or six depending on the person and your mind set.
Who are you, what are your qualifications for making such a broad ranging statement ? Doctor?
Doctors haven't a clue, because, unless they have been on this drug, how the hell would they know?
Oh I get it. They have been educated by the drug company mules (salespeople)
Recommend our drug and you will be in Hawaii in no time and folks that is exactly how it goes...
How does a forum qualify such answers???
And who are you? The commenter Never said they were a doctor. They are simply giving advice and by the sounds of it personal experience advice. The original post isn’t about doctors/sales people or money making conspiracies. Why come on a forum like this if you’re going to go on a rant about the drug companies?
The original poster needed advice on withdrawals, not on how greedy the drug companies are.
Related topics
pristiq, withdrawal, side effect
Further information
- Pristiq uses and safety info
- Pristiq prescribing info & package insert (for Health Professionals)
- Side effects of Pristiq (detailed)
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