My Dr. gradually tapered my dose, but the side effects are horrible. I am having dizziness, mind zaps, chills, emotional craziness & just real tired of feeling like this. I took my last dose 5 days ago. How much longer will this last?
How long do withdrawals from Prestiq last?
Question posted by angbob on 15 Jan 2012
Last updated on 22 February 2021 by DaveyV
The information on this page reflects personal experiences shared by our community members. It is not reviewed for medical accuracy and should not replace professional medical advice.
42 Answers
I had been on antidepressants for approximately 30 years. The last 12 of those years I was on Pristiq 50mg/daily and I had unsuccessfully tried countless times to come of this terrible drug. I could not cope with the withdrawal systems which I will describe as being dangerous due to having to taking those symptoms into a work environment such as mine (Electrical Powerline Worker) or even driving a vehicle.
My doctor switched me onto Lovan (Fluoxetine 20) starting at a dosage of 10mg/day. That was the big advantage taking Lovan over Prozac etc which contains the same drug due to it being in tablet form that you can easily cut with a pill cutter. I stayed on 10mg/day for 2 weeks then lowered to 5mg/day for 3 weeks and then reduced it to 5mg every other day for the final 2 weeks. I have now been med free for approximately 6 months and life could not be better with no evidence of withdrawals or the need to go on any antidepressants for that matter.
Late response I know but here I go 150 mg Pristiq 18 months decided I don't need it any longer being treated for borderline personality disorder bipolar now adhd day 1 nothing day 2 a bit strange day 3 wam got the lot day 4 worse day 5 just the zaps and super dizzy day 6 not there yet cheers
I'm on day 7 since my last dosage. Before that I took pills cut in half for 6 days. Right now most of the side effects have subsided except for the nausea and diarrhea. Yesterday I went to the hospital for IV fluids and other IV meds. I can't imagine surviving like this for much longer.
I was on pristiq 100mg along with 450 welbutrin xl for a few years. I started tapering both off for a few months now (I don't recommend tapering off both at the same time, btw) as I feel I'm strong enough now to go through without meds and wanted it completely out of my system when I start thinking about kids... (I wasn't warned about the whole warning about not being pregnant while on pristiq prior to taking this drug)
I switched to 50 mg of pristiq daily for a few weeks but when I tried to completely get off it, the headaches and nausea was bad so I did it every other day... (my psych said this was weird but didn't tell me to stop doing it... ) it's been 4 days completely off pristiq (and a couple weeks off welbutrin) now and yeah, it's like I can feel my brain literally trying to adjust to not being on it..
Feels like my brain is swollen and headaches and dizziness have been hell but it's improved from the 1st day so I'm going to wait it out. I'm hoping these side effects don't last much longer... I take an advil occasionally on days the headaches are too unbearable for me to get through work.
Does anyone else have body/muscle aches on their head and shoulder area when trying to get off these meds? I'm wondering if it's a side effect of getting off the meds or it's completely unrelated.. I thought at first it was my pillow or bed, but I've had no problems with that before..
Hi. You came off both drugs very fast. It is quite dangerous to actually skip days because it throws your brain into withdrawal every other day. A slow taper is recommended. By using a compounding pharmacy is the best way. I have found that those who wean too fast usually end up right back on Pristiq or something else because the withdrawals are so bad and can show up months down the road. You can Google side effects from weaning off Pristiq. They are different from everyone. There are also Facebook support pages if you are interested. Good luck.
I have been off Pristiq for 10 days and I am so tired all I want to do is sleep all day. It is not a tiredness in my physical body - but a tiredness in my mind - completely cloudy and foggy in the mind. I never sleep during the day, I can rest but never sleep. But I have been sleeping during the day after coming off this medication. I also have mental confusion and find it hard to concentrate on tasks. I have been getting chills and the brain zaps are terrible, I literally feel like there is something crawling around it my mind and my head gets itchy. I have also had many crying outbursts. I hope that things start to improve soon.
Hi suntoshine. How quickly did you wean off Pristiq? I have learned that a very slow taper is the way to go. Your brain needs time to heal with every drop in dosage. I am weaning about 10% each month by using a compounding pharmacy. I have felt a bit of m melancholy at times and a bit of anxiety but none of the other awful side effects. It will take me almost a year and a half to completely wean but I feel it's the healthiest way for me. Good luck.
I have been on 50 mg of Pristiq for five years. I have finally decided it is time to stop. I have CHF and do not want to continue taking this drug for the rest of my short life.
I am glad I found this site which confirmed the withdraw symptoms which I have been able to mitigate with Tylenol. I have been off the drug for two weeks. I will continue to tolerate the side effects until they disappear.
I saw your post from 5 years ago and I'm coming off of Pristiq for anxiety. I'm wondering if you ever found a medication to ultimately help you. I was also on Effexor and had to get off of that medication because of the brain zaps. The Pristiq is also giving me brain zaps.
Thank you for your time!
Michelle
Michelle, I saw your post and wanted to chime in if thats ok. Do a Facebook search with Pristiq in the search bar and you will find a couple of good pages that have been really helpful to the weaning process. The thing with this particular SNRI is that it is very difficult to come off of. Doctor's only know what the drug reps tell them regarding the weaning process and it is such a huge money maker for them, they really don't want you off this drug. Weaning must be done so slowly that it will require either a compounding pharmacy or a jewelry scale so you can crush the tablets, weigh them out and take it every 12 hours because crushing the tablet loses the extended release chemical. Dropping by 5 to 10% every 2 to 4 weeks is what is recommended and only drop again once your brain has stabilized. The awful side effects is what puts most people right back on this drug or another because they can't handle the discomfort. I am down to 11mg and have never experienced one single brain zap. Hope this helps.
Hey all. I have been coming off 400mg of Pristiq over the last month (reducing by 100 a week) and as of two days ago, I am not taking again Pristiq. It is hell, but reminding myself it’s not me it’s the (lack of) medication is helping.
Also I read somewhere in this thread about cutting the pills to smaller doses. BE Careful doing this, the first shrink I saw who recommended this I gave the ass because even I knew that my Pristiq was extended release, and cutting in half gives you the full half dose immediately as one side is no longer coated.
So check that out with your doctor. Hopefully they are smarter than some of the ones I have seen!
Hang in there. Eating properly helped me, I wasn’t eating much at all (just not hungry) and also stay away from coffee etc. lots of water. Flush the poison out!
I was on 100 mg of Pristiq for 3 years. I tapered using 50mg for 6 weeks and took my last tablet 6 weeks ago.
My question is, should I still be experiencing some after effects? I have had a few panic attacks and some feelings of impending doom that have really thrown me off kilter. I had to visit my sister in hospital this week and couldn't fight the urge to just flee the scene. I realise that is a stressful situation under any circumstances, but my inability to calm myself scared me.
I guess I am just seeking some reassurance that this is all part of the withdrawal process. I was told it would take months, I guess they were right?
I also have agoraphobia /(
A doctor placed me on 50 mg Pristiq daily for PMDD. After a few months, he increased it to 100 mg. daily. I was on that for years but decided that I didn't want to take anything that would cause withdrawals if I didn't have it. That's when I started learning that it is a drug from hell. Miss a dose and get dizziness, brain zaps and really bad tinnitus. Actually, my tinnitus increased when I began taking the drug, but I didn't catch the connection until later. The tinnitus is super loud when NOT taking the drug. Anyway, I have done a really slow taper. But the only thing that got me through decreasing the dose was 2-week organic juice fasts. For some reason, the super nutrition lessens the wd symptoms. I cut down to 50 mg for a year, then 25 mg daily for a year. Now, I'm on day 3 of no Pristiq. I am doing organic juice, but still eating some food. It hasn't been as problem-free, so today I'm stopping the food and just doing organic juice.
I do have LOUD tinnitus and a little dizziness, but no brain-zaps! The zaps were always BAD with a missed dose, so this is interesting. I do have some chills and all-over tingling, but that could also be because I missed a few doses of Estroven. (Menopause --- a whole other nightmare, lol!) Anyway, for me, the organic juicing really helps. And not just with Pristiq WD. It helps getting off any drug that causes wd symptoms when not taken. I read that someone on here was still having symtpoms years after getting off Pristiq. I hope that's not my experience. I will post again when the symptoms stop.
Lighterdays, if you can find a compounding pharmacy you can taper down slower. 25mg to zero is a huge jump! I have been tapering since the beginning of May from 50. I am now on 9mg compounded. I will stay on this for a month then drop another 3mg. and continue dropping by 3mg til I hit zero. I have minimal w/d symptoms this way. Usually days 2-5 after a drop I experience a slight headache and some nausea. After that I'm fine. I also am trying a plant based diet as well as juicing. Good luck! This is an awful drug! It masks the symptoms of menopause which is the only good thing about it. But once you begin weaning, all the menopausal symptoms come right back!
Tchatterbug, if Pristiq masks the symptoms of menopause, I am in deep trouble getting off of it. I had heard about compounding the drug, but never checked into it because I also heard it was very expensive. Thank you for your comments.
For one thing, my pharmacist told me you shouldn't break or cut the Pristiq in half or quarters if you're trying to get off, since it's time released and you make get a big bolus of the medication or none at all. She told me (off the cuff) you would have been better staying on the Effexor and opening up the capsule and emptying out the little "balls" inside, a few more at a time each day. Regardless, if you hang in there, the effects of withdrawing will disappear over 2 weeks at the longest. I took my vacation (woo hoo) during that time so I wouldn't have to concentrate as much. If you are going on another medication, make sure your pharmacist tells you about avoiding serotonin syndrome. Pharmacists, I find, have so much more information about medication that physicians.
I am 10 days into a 100mg taper. Been off all together for two days. This is the most harrowing experience I could ever imagine. I'm under the guidance of one of the best psychiatrists in our area for Med management. I have taken Zoloft, Lexapro and others for 20 years and tapered with minimal discomfort. I was on Pristiq for 2 1/2 years. The first 3 days of the taper were uncomfortable but manageable. Days 4-6 I experienced hyper mania and insomnia beyond my wildest imagination. At day 9 and 2 days Pristiq free I am now at the point of crying fits, wildly terrifying dreams during very sporadic moments of what feels like sleep but is more like a psychedelic trance, and I am terrified at what tomorrow will bring. I am determined to proceed but having a community right now could be my savior. I am afraid of estranging the few people who love me through this process.
My kids have witnessed wild mood swings, irritatability and debilitating tears. I'm a single mom and have to keep working during this process and do not have the financial resources or time for self care. So I'm plowing ahead. I do everything everyone recommends - workout, swim, eat well, stay focused, reach out at moments of despair, and still each day is worse from both the withdrawal symptoms and great unknown. What can I expect next, how much longer will this last, should I start a new anti anxiety immediately, will I ever be happy again? Will I make it? I have to make it so please throw me a rope. Thank you.
Hi. How is your taper going? I am tapering as well. It's been a tough road. I am down to 15mg daily of Pristiq but have to pay out of pocket to get it compounded to lower doses. I have dealt with anxiety being the worse side effect but noticing a slew of others too. I'd love to hear how you are doing though.
"wildly terrifying dreams during very sporadic moments of what feels like sleep but is more like a psychedelic trance" this describes last night for me perfectly. My dreams were vivid and intense since starting pristiq but last night was something else. Day 3 off pristiq 50mg -_-
How has it been going for you?
I have been tapering 100 down to 50mg over the last month and a half. Took my last 50mg of pristiq 3 days ago and first 20mg Prozac, which I'm switching to, this morning. I've had nausea, zaps, dizziness, random crying and general inability to function since day 2/yesterday, and don't feel safe to drive. Hoping this becomes bearable within a couple more days or that the Prozac somehow helps pristiq withdrawal!?
Guhhh.
I'm so glad I found this information. I've only been taking it for 3 days and I already notice weird side effects like loss of appetite, diarrhea, mood swings, change in sexual mood, etc.. I was prescribed Pristiq for my anxiety and depression which came out of no where. My dr also prescribed me lorazepam which I only took for a few days and stopped. I've started to meditate and really observe my panic and anxiety when it comes on and I actually welcome it. When you accept it and stop trying to resist it, you realize how much stronger you are than the anxiety. I've started exercising, cut out caffeine and sugar, spend more time outside, and started taking CBD (one of the active chemicals in cannabis that doesn't get you high but helps with pain, insomnia, anxiety, depression, seizures, tremors). I'm glad I found this information early so I can discontinue it only 3 days after starting it. Thank you all for you feedback and I hope you're all doing great.
I started on Pristiq for Cyclothymia disorder in July 2015. It worked really well for me in controlling anxiety, paranoia and emotional stability. On 18/12/2016 I reduced my intake from 100mg to 75mg by taking 11/2 50mg tablets. On 15/01/2017 I dropped to 50mg. And on 15/02/2017 I stopped taking Pristiq completely. The obvious side effects of mind zaps and d swing were apparent in the first 5 days and quite intense. I am now 12 days without Pristiq and the side effects have reduced considerably however I find that from time to time I still get bouts of mind zaps and headaches but all in all getting better. Pristiq has helped me but I found myself somewhat emotionless, apathetic, having a significant reduction in sex drive and lacking drive and energy. Now that I'm off it I can feel so much more intensely. I have noticed a minor increase in anxiety and paranoia but being on Pristiq helped me recognise the reason behind this and now find it easier to control. Overall so far Pristiq disregarding the side effects has had a positive impact on my life.
Hey... I was on pristiq for one year after unsuccesfully trying lexapro for another year... I had never had depression before and I was diagnosed with post traumatic anxiety... My doctor was great all the way and the day came for me to quit we discussed the best option and he told me to take one every other day for 2 weeks and then one every 3 days for 2 weeks... During the first two weeks I had zero withdrawal symptoms thank god and there were days I felt very euphoric, like super happy over the top happy lol so I called him and my doc told me to quit for good after my first two weeks.. I was scared cause when I tried quitting lexapro it was hell but it went perfectly well... Ive been hitting the gym since day one of my tretment and I guess it makes a lot of difference... Its been 4 or 5 months since my last dose and its great... Ive been going out with my friends enjoying my family, my job... I'm applying for a new job actually and I have lost 6kg since then so yeah I wanted to reply cause there's always so many horror stories and it can be good good luck
Related topics
pristiq, withdrawal, side effect
Further information
- Pristiq uses and safety info
- Pristiq prescribing info & package insert (for Health Professionals)
- Side effects of Pristiq (detailed)
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