How does Buspirone help with depression?
Question posted by Ckford on 2 July 2023
Last updated on 23 August 2023
3 Answers
Not officially but it can help some
I have been diagnosed with depression as well as anxiety disorders, and I do find that buspirone does help with my depression as well. I am antidepressant treatment resistant, but between my buspirone and clonazepam I find they help a great deal with my depression.
Buspirone is primarily used for generalized anxiety disorders. It may help relieve depression associated with anxiety and possibly as adjunct therapy with other medications for unipolar depression.
"Doctors typically advise Buspar as a second-line treatment for people with depression, after they have tried first-line antidepressant medications such as selective serotonin reuptake inhibitors (SSRIs)."
"Buspar works by binding to serotonin (and sometimes dopamine) receptors in the brain.
Serotonin is a chemical messenger (neurotransmitter) that sends signals between cells to help regulate mood. People with mental health conditions such as depression typically have an imbalance of serotonin and other neurotransmitters."
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Further information
- Buspirone uses and safety info
- Buspirone prescribing info & package insert (for Health Professionals)
- Side effects of Buspirone (detailed)
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