I am taking 600 mg of gabapentin 3x a day as a mood stabiliser for my bipolar 2 disorder. It works beautifully for that. I feel great. I feel upbeat but calm at the same time, if that makes sense. The only problem is that it's causing sexual dysfunction. I'm a woman in my early 30s and could previously have multiple orgasms every time and a high sex drive. My sex drive is normal now but I absolutely cannot have an orgasm, even if I try it on my own. It's so frustrating because the drive is there but I can't do anything about it. I'm just... numb. Anything I can do to help this? It's a really big problem and frustrating for my partner as well.
Gabapentin- female anorgasmia/sexual dysfunction?
Question posted by GingerAsh on 28 Jan 2015
Last updated on 15 February 2023 by Monami2457
I've even gotten to the point where I don't take it on a day I know he'll come over to visit, in hopes that I don't have the problem, but that's really unhealthy for me.
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31 Answers
I've been on an increasing dosage schedule of gabapentin for the past 5 weeks, at this point up to (3) 300 mg capsules 3 times per day, but with no easing of my lower back pain. In addition to not getting relief from my pain, I'm unable to achieve orgasm. This has never happened in all of my 70 years of having a high sex drive and easy, frequent orgasms. I suppose I could tolerate that if I had to, but at the same time, the medication causes me to be in an almost constant state of sexual arousal. This is incredibly frustrating! I'm going to tell my doctor that I want to discontinue the gaba and gradually reduce the dosage till I'm off it entirely.
Ladies, it happens to men to with this same med. The problem is I take it for chronic pain and cannot stop. There are several other meds I take that do this too. That includes my opioids.
The only way I have found around it is to try naughty things, like in the den with no blinds down. That little edge sometimes helps.
I am taking 3600mg of gabapentin daily for small and large fiber neuropathy. I started taking it 15 years ago and the desire is there but the orgasm is not. Someone mentioned a medication for that’s just for men. Is there anything for women yet??? I can’t stop the gabapentin because my neuropathy is bad. And lyrica does not work for neuropathy.
There are a few medications available for women including oral and topical and yes, some ladies are helped with sildenafil (Viagra). Another possibility is bupropion (Wellbutrin).
It's not an embarrassing topic so give your doctors a call.
I am also on 1800mg of Gabapentin daily for neuropathic pain and am unable to orgasm with my husband or on my own.
We are very happily married and have a very healthy sex life, so I know it's the Gabapentin.
I have previously been prescribed all the other usual medications for my nerve pain, but gabapentin has been the most effective so far.
I am in my mid fifties and just don't know what to do. My pain relief or my sex life!!!
Genitourinary
Common (1% to 10%): Incontinence, impotence
Uncommon (0.1% to 1%): Hematuria, dysuria, urinary frequency, cystitis, urinary retention, vaginal hemorrhage, amenorrhea, dysmenorrhea, menorrhagia
Frequency not reported: Sexual dysfunction (including changes in libido, ejaculation disorders, and anorgasmia)[Ref]
This response addresses something I'm wondering about, then it specifically addresses the original poster's question:
I'm not only in the medical field, but I'm also on gabapentin. I've never been multi-orgasmic, so I do wonder if a person is and is very easily, how if it would be worth it to be on any medication that takes away that ability would be worth it unless all other medications have failed and the illness is severe. I mean, if one is multiorgasmic and has a moderate pain condition, would having orgasms throughout the day be enough to help w/pain and provide enough pleasure to outweigh the chronic pain? I've never had a patient on any orgasms-stopping medication who was ordinarily highly & easily multiorgasmic.
What is the most extreme negative sexual reaction gabapentin is causing? Someone went from 10+ orgasms to 0, but has it been worse for anyone else (e.g., 15+ powerful orgasms in an hour to 0)? Has anyone who's extremely orgasmic (quantity and quality) had a decrease to something like single orgasms, rather than 0?
To the original poster, with a number of other options for BPD, did you ultimately go w/another medication (e.g., lithium or FDA approved for bipolar2 Seroquel and Seroquel XR) and do much better?
I started gabapentin roughly 5 weeks ago and for the first time in my life, I haven't been able to orgasm at all, not only that but my libido has plummeted and I essentially feel numb down there. I have been on a plethora of other drugs for my mental health (I'm currently taking Gaba for nerve pain), one of them being Seroquel like you mentioned but nothing has ever interrupted my ability to orgasm. I only discovered this connection between anorgasmia and Gaba after I googled to see if this new drug that i was taking could have been the issue, especially since it targets nerves, I thought it was a logical jump to assume it could also effect ability to feel pleasure, and sure enough, looks like I'm onto something.
This isn't necessarily an answer but a comment. I too take Neurontin for various reasons and I also experience sexual dysfunction. I'm a 25 year old female and have never had an issue prior to the medication either. I have a healthy drive and am able to orgasm multiple times, generally pretty easily. I usually just need light stimulation to get there but I've noticed anytime I use Neurontin I am completely unable to orgasm. I can't keep my head focused on it for starters, and even if I get there mentally my body just doesn't want to work for me. I don't produce any of my own lubrication and I just absolutely cannot orgasm until the medication is out of my system. This happens to everyone I know that takes Neurontin, my ex (male, 32 years old) as well had the issue. He couldn't stay hard or reach orgasm. I have no idea why Neurontin does this.
All I can think of is that it blocks your nerve endings and our clits are basically a giant nerve and for some reason the medication is inhibiting our clitoris' from reaching orgasm because the nerve is blocked or numbed. It absolutely sucks. I've never found a solution other than stopping the medication for a day or two and having an orgasm and then going back on it. Or having an orgasm straight away in the morning when I wake up, when the Neurontin is no longer at its peak and it's about worn off or at least dulled, and then just taking it after I have reached orgasm. That works for me. I realize it's quite a predicament. You either take the medication that you so need for various reasons and can't cum or you don't take the medication you need and sacrifice your mental health for your sexual health. The only thing I've found to manage both taking the meds and having an orgasm is to have my orgasm in the morning prior to taking the medication. I'm sorry. It happens to almost everyone who takes this medication. Not sure if they've discovered a better solution yet or not. Good luck.
Hello. Im looking to hear from someone who has experienced this and still continued the drug regardless for a year or more and still got their ability to orgasm back after withdrawal. Due to pain I have continued with the drug for 1.5 years after getting anorgasmia quickly after starting the drug. I too had a very high sex drive before, could reach orgasm within 5 minutes and have multiple, up to ten orgasms in a row. I'm worried that I might have caused permanent damage by not quitting the drug when my doctir told me that it could be causing the problem.
I am in the same boat. 37yr old male taking 900mg a day for severe hip pain and have never in my life had an issue climaxing and now it’s impossible and very frustrating. Have at least two more months before surgery and refuse to take prescription narcotics.
Hello gingerash. I am responding 5 years after your post in case anyone else is looking for this answer. I too- had a beneficial experience from gabapentin in that it did help nerve pain. I also liked feeling more calm- although a bit sloppy (so watch any emails or contracts you might write). However the main and biggest problem- and reason I eventually had to get off the gabapentin was because I could not get off (pardon the pun). I too am a woman but in my mid 50's. Never had a problem with having orgasm with my partner or alone. Until I went on gabapentin three times a day..I think having it just one and a lower dose at night might be ok (say 300 mg at night) but even that- I would not do now with consistency as absolutely, I could not orgasm. Sex still felt good- so that was ok. It did not turn off sexual desire, just the ability to orgasm. It is like your special parts are under a pillow. Anyway I had to get off of it.
That's heaps too much isn't it? I'm supposed to take 300mg 3* day. Today is my first day. I just opened the first capsule and swished it down with a shot of vodka. So now I wait.you guys have scared me!
I have this same problem on gabapentin. Ive been on it roughly 3 weeks and can not orgasm. Its because it numbs your nerves and prevents hyper sensitivity. So dont let these ppl think its your partner or something else its not. Its the gabapentin
Hello, GingerAsh ~
I hope you've been sticking by your own knowledge of your body in being sure that it's the gabapentin causing the anorgasmia. Even at a very low dosage, I was hit with the same issue, one I'd previously experienced with other medications, namely antidepressants. But I found a fix that works very well for me, although I told my doctor I didn't want to continue with the gabapentin for other reasons. So, have you ever heard of maca root and/or tribulus fruit? Maca 500 mg (Viva Naturals) and tribulus 1300 mg (Biogreen Labs) are the two most recent brands I've gotten on Amazon Prime. Read the reviews, and you'll be amazed! I really hope this helps you if you haven't already found relief.
I have the same problem. I’m fortunate that I only need to take it once at night (restless leg syndrome), so I can achieve orgasm in the afternoon. But think about it, I take it for RLS, a spasm (simplistic explanation). What is an orgasm? A spasm. (Again, simplistic). Don’t let anyone tell you it’s in your head! It’s the only med that works for me, but I have a workaround. I hope you all find your solution!
I had this problem with both Lyrica and Cymbalta. My husband and I could not figure out what was wrong with me. I still think he actually thought that I wasn’t interested in him anymore. Oh but I was! I was so much in love with him and him with me... before these horrible medications played havoc with our lives. We were each other’s best friend. I had almost every side effect that’s on the list and some that are not even on the list yet. They caused me to be in more pain than what I was already in. They caused me to feel anxious, confused, forgetful and depressed. I was living in a fog and I was so tired all the time. These medications changed who I was. We have divorced now (I will always believe that these medications were a huge part of it). I didn’t find out that I couldn’t have an orgasm because of these medications until after we were divorced so he will probably never know that now.
I still love him and I miss him every day but he has gone on with his life without me. I am not alone though because I have my 5 amazing children, their partners and 9 awesome grandchildren. I would never have made it through without them. I’ve tapered off Lyrica and I’m almost off Cymbalta now. Almost every side effect is gone. I’m hoping to be completely off by 2019 and I will start working at getting healthy again and getting ‘me’ back. I’m hoping and praying that I will find someone to love again. I’m thankful that after all I’ve been through I still believe in love. Please take care everyone and I wish you all the best. Cindy
I understand what you are going through. I'm going through the same thing. Doing what I do by myself... it's not working for me now, since I started this high dose of Neurontin.
Related topics
bipolar disorder, gabapentin, sexual dysfunction, female, disorder
Further information
- Gabapentin uses and safety info
- Gabapentin prescribing info & package insert (for Health Professionals)
- Side effects of Gabapentin (detailed)
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