Does Duloxetine make you more anxious at first and do side effects fade after a while?
Does Duloxetine make you anxious?
Question posted by dawn2210 on 6 May 2021
Last updated on 24 August 2021
Answers
I was on Cymbalta (Duloxetine) for Trigeminal Neuralgia (nerve pain). I ended up taking it over 10 years but I kept getting worse. I thought it was the TN getting worse but I did some research on Cymbalta and I realized that everything was from side effects from the medication. Shortly after starting Cymbalta the anxiety, depression and suicidal thoughts began. I never had any of these before I started taking Cymbalta. The weight gain was horrible and the brain fog and being forgetful was really hard. I thought I was getting dementia. The list of other side effects I experienced is very long and they not only didn’t go away, they kept getting worse. I ended up bedridden for 3 years of the time I was taking it. Once I found out everything was because of side effects from Cymbalta I decided to get off it but I didn’t know how long it would take to taper off. Most people don’t know the long list of side effects from Cymbalta, especially if they’ve never taken it and they have no idea how hard it is to get off of. I’ve been completely off for a while now and every side effect is gone. I’m not just existing now, I have a life again.
Hi, I am tapering off of Zoloft and starting cymbalta. I am so nervous. I always get the side affects. Almost always. I guess I need to prepare.
Hi, I am tapering off of Zoloft and starting cymbalta. I am so nervous. I always get the side affects. Almost always. I guess I need to prepare.
I really do hope you do better with Cymbalta than I did. One thing I meant to mention was the side effects crept up on me so please be on the lookout for them. You can find the entire side effect list online. I wish you all the best.
Yes, at first it can make some people anxious and you must inform your DR..
Regarding the side effects they work themselves out and subside between one week to 10 days, if the side effects persist contact your DR., perhaps you need a dose adjustment or what your Dr. sees what is more suitable for you.
Hi, Dawn!
Masso's comment is spot on. New or increased anxiety is a common side effect of duloxetine (and most other antidepressant/anxiolytics) that affects about 1~10% of users. It should subside quickly but do keep your doctor informed.
Best regards and I hope you feel better soon!
and thank you for your valuable comment.
Stay safe my friend, masso
It's good seeing you around lately!
Take care, my friend.
@ dawn.
PS, The benefits of the medication far outweigh the risk of side effects for most people.
Thank you so much for replying, I feel reassured and I am starting them tomorrow
Please post an update if you have any questions or concerns. Have a pleasant journey to good health!
Hello,
I have been on these 2 days and so far I don’t feel any major side effects.
I do feel in a daze though, will this pass?
Thanks
Dawn
It should soon as most side effects resolve over a few days to a week or so... and they generally lessen each day.
Be patient and you will start to feel the effects of the medication in a beneficial way usually in the first week or two.
Thank you, I will keep going..thanks so much.
Related topics
anxiety, generalized anxiety disorder, duloxetine, side effect
Further information
- Duloxetine uses and safety info
- Duloxetine prescribing info & package insert (for Health Professionals)
- Side effects of Duloxetine (detailed)
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