Codeine Alternatives Compared
| Codeine | Tramadol | Gabapentin |
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| Codeine | Tramadol | Gabapentin |
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Prescription only
Codeine is an effective pain reliever; however, it is addictive, may cause constipation, and its pain-relieving effects vary markedly between individuals. Codeine should only be used for pain relief... View more |
Prescription only
Tramadol is a strong opioid pain relieving medication that may be used to treat moderate to severe general and nerve-related pain. Tramadol may be habit-forming and misuse can cause addiction... View more |
Prescription only
Gabapentin is an anticonvulsant with pain-relieving effects that may be used to treat certain seizure disorders or relieve nerve pain. Common side effects include dizziness or drowsiness and it may... View more |
Related suggestions |
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| More about Codeine | More about Tramadol | More about Gabapentin | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Codeine has an average rating of 8.0 out of 10 from a total of 68 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 13% reported a negative effect. |
Tramadol has an average rating of 7.0 out of 10 from a total of 1861 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 24% reported a negative effect. |
Gabapentin has an average rating of 7.2 out of 10 from a total of 2545 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Side Effects | ||||||||||||||||||||||||||
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See also: codeine side effects in more detail. |
See also: tramadol side effects in more detail. |
See also: gabapentin side effects in more detail. |
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| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all codeine prices |
View all tramadol prices |
View all gabapentin prices |
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| Dosage Forms Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
ConZip, Qdolo, Tramadol Hydrochloride ER | Fanatrex, Gabarone, Gralise, Neurontin | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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3.5 hours |
5.2 hours |
6 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 508 drugs are known to interact with codeine:
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A total of 688 drugs are known to interact with tramadol:
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A total of 270 drugs are known to interact with gabapentin:
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| First Approval Date | ||||||||||||||||||||||||||
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July 16, 2009 |
March 03, 1995 |
December 30, 1993 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.