Comparing Codeine vs Promethazine
Codeine | Promethazine |
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Codeine | Promethazine |
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Prescription only
Codeine is an effective pain reliever; however, it is addictive, may cause constipation, and its pain-relieving effects vary markedly between individuals. Codeine should only be used for pain relief... View more |
Prescription only
Promethazine may be used to relieve allergy symptoms and nausea. Sedation is the main side effect and it may interact with several other drugs including antidepressants, antipsychotics, and other... View more |
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More about Codeine | More about Promethazine | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Codeine has an average rating of 7.9 out of 10 from a total of 66 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 13% reported a negative effect. |
Promethazine has an average rating of 7.2 out of 10 from a total of 377 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 21% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: codeine side effects in more detail. |
See also: promethazine side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all codeine prices |
View all promethazine prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
N/A |
Adgan, Anergan 50, Antinaus 50, Phenadoz, Promethegan | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
3.5 hours |
16 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 505 drugs are known to interact with codeine:
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A total of 685 drugs are known to interact with promethazine:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
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First Approval Date | |||||||||||||||||
July 16, 2009 |
March 29, 1951 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.