Xcopri: Uses, How It Works, and Common Side Effects

Xcopri is used to treat partial-onset seizures in adults to help reduce the number of seizures. Some people may have their seizures reduced to zero.

It is an anticonvulsant that can be used on its own or can be used together with other anti-seizure medications.

This medicine is available as tablets which can be swallowed whole, or it may be crushed and mixed with water and given by mouth as an oral suspension or administered via a nasogastric tube.

These tablets should not be stopped suddenly, instead the dose should be gradually decreased over at least 2 weeks, following doctors’ instructions.

It is not known exactly how this medicine works to reduce the frequency of partial-onset seizures but may be because it inhibits voltage-gated sodium channels and positively affects the γ-aminobutyric acid (GABA) ion channel.

Xcopri was FDA-approved on the 21st of November 2019.

Common side effects may include feeling tired, dizziness, drowsiness, double vision or headaches. Other serious side effects may occur including increase risk of suicide, multiorgan hypersensitivity, and QT shortening which affects the heart.

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Always consult with your healthcare provider.