Micardis HCT Side Effects

Generic name: hydrochlorothiazide / telmisartan

Medically reviewed by Drugs.com. Last updated on Sep 23, 2024.

Note: This document provides detailed information about Micardis HCT Side Effects associated with hydrochlorothiazide / telmisartan. Some dosage forms listed on this page may not apply specifically to the brand name Micardis HCT.

Applies to hydrochlorothiazide / telmisartan: oral tablet.

Important warnings This medicine can cause some serious health issues

Oral route (tablet)

Drugs with direct action on the renin-angiotensin system can cause injury or death to the developing fetus when used during pregnancy.

Stop therapy as soon as possible if pregnancy occurs.

Common side effects of Micardis HCT

Some side effects of hydrochlorothiazide / telmisartan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• body aches or pain
• cough
• difficulty breathing
• dizziness
• ear congestion
• fever
• headache
• loss of voice
• runny or stuffy nose
• sneezing
• sore throat

Less common side effects

• acid or sour stomach
• back pain
• belching
• blistering, peeling, loosening of the skin
• cough producing mucus
• diarrhea
• heartburn
• hoarseness
• indigestion
• itching
• joint pain
• loss of appetite
• muscle aches and pains
• pain or tenderness around the eyes and cheekbones
• rash
• red irritated eyes
• red skin lesions, often with a purple center
• shivering
• sores, ulcers, or white spots in the mouth or on the lips
• stomach pain
• sweating
• tender, swollen glands in the neck
• tightness in the chest
• trouble sleeping
• trouble swallowing
• voice changes

Incidence not known

• decreased interest in sexual intercourse
• inability to have or keep an erection
• loss in sexual ability, desire, drive, or performance

Serious side effects of Micardis HCT

Along with its needed effects, hydrochlorothiazide/telmisartan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking hydrochlorothiazide / telmisartan:

Less common side effects

• bladder pain
• bloody or cloudy urine
• blurred vision
• confusion
• decreased urine
• difficult, burning, or painful urination
• dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
• dry mouth
• fainting
• fast, pounding, or irregular heartbeat or pulse
• frequent urge to urinate
• increased thirst
• loss of appetite
• lower back or side pain
• muscle pain or cramps
• nausea or vomiting
• numbness or tingling in the hands, feet, or lips
• seizures
• sudden sweating
• trouble breathing
• unusual tiredness or weakness

Rare side effects

• chills
• cold sweats
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

Incidence not known

• persistent non-healing sore
• pink growth
• reddish patch or irritated area
• shiny bump
• white, yellow or waxy scar-like area

For healthcare professionals

Applies to hydrochlorothiazide / telmisartan: oral tablet.

General adverse events

The most common adverse effect was upper respiratory tract infection.^[Ref]

Respiratory

• Common (1% to 10%): Sinusitis, upper respiratory tract infection, cough
• Uncommon (0.1% to 1%): Dyspnea
• Rare (less than 0.1%): Bronchitis, pharyngitis, respiratory distress, pneumonitis, pulmonary edema

Hydrochlorothiazide:

• Very common (10% or more): Upper respiratory tract infection (10%)
• Common (1% to 10%): Sinusitis
• Frequency not reported: Respiratory distress, pneumonitis, pulmonary edema

Telmisartan:

• Common (1% to 10%): Sinusitis, upper respiratory tract infection
• Uncommon (0.1% to 1%): Cough
• Frequency not reported: Asthma, rhinitis, dyspnea, epistaxis
• Postmarketing reports: Interstitial lung disease^[Ref]

Other

• Common (1% to 10%): Fatigue, influenza-like symptoms, pain
• Uncommon (0.1% to 1%): Chest pain

Hydrochlorothiazide:

• Common (1% to 10%): Fatigue, influenza-like symptoms
• Frequency not reported: Weakness, pyrexia

Telmisartan:

• Common (1% to 10%): Fatigue, influenza-like symptoms
• Uncommon (0.1% to 1%): Asthenia
• Frequency not reported: Earache, fever, malaise, leg edema, peripheral edema, dependent edema, chest pain
• Postmarketing reports: Weakness, edema, face edema, pain^[Ref]

Nervous system

• Common (1% to 10%): Dizziness, headache
• Uncommon (0.1% to 1%): Syncope, paresthesia, vertigo

Hydrochlorothiazide:

• Common (1% to 10%): Dizziness
• Frequency not reported: Lightheadedness

Telmisartan:

• Common (1% to 10%): Dizziness
• Rare (less than 0.1%): Somnolence
• Frequency not reported: Tinnitus, migraine, hypoesthesia, cerebrovascular disorder, vertigo, paresthesia, hypoesthesia, involuntary muscle contraction
• Postmarketing reports: Headache, syncope^[Ref]

Gastrointestinal

• Common (1% to 10%): Diarrhea, nausea
• Uncommon (0.1% to 1%): Dry mouth, flatulence
• Rare (less than 0.1%): Abdominal pain, constipation, dyspepsia, vomiting, gastritis

Hydrochlorothiazide:

• Common (1% to 10%): Diarrhea, nausea
• Frequency not reported: Sialadenitis, pancreatitis, stomach discomfort, cramping, gastric irritation

Telmisartan:

• Common (1% to 10%): Diarrhea, nausea
• Rare (less than 0.1%): Stomach discomfort
• Frequency not reported: Hemorrhoids, gastroenteritis, enteritis, gastroesophageal reflux, toothache, non-specific gastrointestinal disorder, flatulence, constipation, gastritis, dry mouth,
• Postmarketing reports: Dyspepsia, abdominal pain^[Ref]

Renal

• Common (1% to 10%): BUN increased 11.2 mg/dL or greater, serum creatinine increased 0.5 mg/dL or greater

Hydrochlorothiazide:

• Frequency not reported: Nephritis interstitial, renal dysfunction, renal failure

Telmisartan:

• Uncommon (0.1% to 1%): Renal impairment, acute renal failure^[Ref]

Genitourinary

• Common (1% to 10%): Urinary tract infection
• Uncommon (0.1% to 1%): Erectile dysfunction
• Frequency not reported: Impotence

Hydrochlorothiazide:

• Frequency not reported: Glycosuria

Telmisartan:

• Uncommon (0.1% to 1%): Urinary tract infection
• Frequency not reported: Micturition frequency, cystitis, impotence
• Postmarketing reports: Erectile dysfunction^[Ref]

Hematologic

• Common (1% to 10%): Hemoglobin decreased 2 g/dL or greater
• Uncommon (0.1% to 1%): Hematocrit decreased 9% or more

Hydrochlorothiazide:

• Frequency not reported: Aplastic anemia, hemolytic anemia, bone marrow depression, leukopenia, neutropenia, agranulocytosis, thrombocytopenia

Telmisartan:

• Uncommon (0.1% to 1%): Anemia
• Rare (less than 0.1%): Eosinophilia, thrombocytopenia, hemoglobin decreased^[Ref]

Cardiovascular

• Uncommon (0.1% to 1%): Tachycardia, arrhythmias, hypotension, orthostatic hypotension

Hydrochlorothiazide:

• Frequency not reported: Vasculitis necrotizing

Telmisartan:

• Uncommon (0.1% to 1%): Bradycardia
• Frequency not reported: Palpitation, angina pectoris, abnormal ECG, flushing, hypertension
• Postmarketing reports: Atrial fibrillation, congestive heart failure, myocardial infarction, blood pressure increased, hypertension aggravated, hypotension, postural hypotension^[Ref]

Musculoskeletal

• Uncommon (0.1% to 1%): Back pain, muscle spasm, myalgia
• Rare (less than 0.1%): Arthralgia, muscle cramp, pain in limb, blood creatine phosphokinase increased
• Frequency not reported: Leg pain, cramps in legs
• Postmarketing reports: Exacerbation or activation of systemic lupus erythematosus

Hydrochlorothiazide:

• Frequency not reported: Lupus-like syndrome, muscle spasm

Telmisartan:

• Rare (less than 0.1%): Arthrosis, tendon pain, tendonitis, tenosynovitis
• Frequency not reported: Arthritis, arthralgia, leg pain, leg cramps, myalgia
• Postmarketing reports: Back pain, muscle cramps, creatine phosphokinase increased, rhabdomyolysis^[Ref]

Metabolic

• Uncommon (0.1% to 1%): Hypokalemia, blood uric acid increased
• Rare (less than 0.1%): Hyperuricemia, hyponatremia

Hydrochlorothiazide:

• Frequency not reported: Diabetes mellitus inadequate control, anorexia, appetite decreased, electrolyte imbalance, hypercholesterolemia, hyperglycemia, hypovolemia, triglycerides increased, hyperuricemia

Telmisartan:

• Uncommon (0.1% to 1%): Hyperkalemia
• Rare (less than 0.1%): Hypoglycemia in diabetic patients
• Frequency not reported: Diabetes mellitus, gout, hypercholesterolemia
• Postmarketing reports: Uric acid increased^[Ref]

Psychiatric

• Uncommon (0.1% to 1%): Anxiety
• Rare (less than 0.1%): Depression, insomnia, sleep disorder

Hydrochlorothiazide:

• Frequency not reported: Restlessness

Telmisartan:

• Frequency not reported: Nervousness, insomnia, anxiety, depression^[Ref]

Dermatologic

• Rare (less than 0.1%): Angioedema, erythema, pruritus, rash, hyperhidrosis, urticaria
• Frequency not reported: Sweating increased

Hydrochlorothiazide:

• Frequency not reported: Photosensitivity reactions, skin vasculitis, toxic epidermal necrolysis, cutaneous lupus erythematosus-like reactions, reactivation of cutaneous lupus erythematosus, erythema multiforme, Stevens-Johnson syndrome, exfoliative dermatitis, purpura, urticaria

Telmisartan:

• Rare (less than 0.1%): Eczema, drug eruption, toxic skin eruption, toxicoderma, rash, angioedema
• Frequency not reported: Dermatitis, sweating increased, pruritus
• Postmarketing reports: Urticaria, erythema^[Ref]

Hepatic

• Rare (less than 0.1%): Abnormal hepatic function/liver disorder, hepatic enzyme increased
• Frequency not reported: Serum bilirubin increased

Hydrochlorothiazide:

• Frequency not reported: Jaundice hepatocellular, jaundice cholestatic

Telmisartan:

• Postmarketing reports: Abnormal hepatic function/liver disorder^[Ref]

Ocular

• Rare (less than 0.1%): Visual disturbance, vision blurred

Hydrochlorothiazide:

• Frequency not reported: Xanthopsia, acute myopia, acute angle-closure glaucoma, transient blurred vision

Telmisartan:

• Frequency not reported: Conjunctivitis, abnormal vision^[Ref]

Immunologic

Hydrochlorothiazide:

• Frequency not reported: Anaphylactic reactions, hypersensitivity, allergy

Telmisartan:

• Rare (less than 0.1%): Sepsis, hypersensitivity, anaphylactic reactions
• Frequency not reported: Allergy, infection, fungal infection, abscess, otitis media^[Ref]

Further information

Micardis HCT side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer