Lemborexant Side Effects

Medically reviewed by Drugs.com. Last updated on Jul 10, 2024.

Applies to lemborexant: oral tablet.

Serious side effects of lemborexant

Along with its needed effects, lemborexant may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking lemborexant:

More common side effects

• sleepiness or unusual drowsiness
• unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
• unusual tiredness or weakness

Less common side effects

• temporary inability to move or talk while you are going to sleep or waking up

Rare side effects

• changes in behavior
• discouragement
• feeling sad or empty
• irritability
• lack of appetite
• loss of interest or pleasure
• seeing, hearing, or feeling things that are not there
• thoughts of killing oneself
• trouble concentrating

Other side effects of lemborexant

Some side effects of lemborexant may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• headache

For healthcare professionals

Applies to lemborexant: oral tablet.

General adverse events

The most commonly reported side effects included somnolence, fatigue, headache, abnormal dreams and/or nightmares.^[Ref]

Nervous system

• Very common (10% or more): Somnolence (up to 10.5%)
• Common (1% to 10%): Headache, sleep paralysis
• Frequency not reported: Cataplexy-like symptoms, lethargy^[Ref]

Psychiatric

• Common (1% to 10%): Abnormal dreams, nightmare
• Frequency not reported: Complex sleep behavior, hypnagogic hallucinations, suicidal ideation, worsening of depression^[Ref]

Other

• Common (1% to 10%): Fatigue
• Frequency not reported: Sluggishness^[Ref]

Frequently asked questions

• What are the strongest sleeping pills?
• Is Dayvigo addictive?

Further information

Lemborexant side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer