Dried Factor VIII Fraction Type 8Y Side Effects

Generic name: antihemophilic factor/von willebrand factor

Medically reviewed by Drugs.com. Last updated on Dec 14, 2024.

Note: This document provides detailed information about Dried Factor VIII Fraction Type 8Y Side Effects associated with antihemophilic factor/von willebrand factor. Some dosage forms listed on this page may not apply specifically to the brand name Dried Factor VIII Fraction Type 8Y.

Applies to antihemophilic factor/von willebrand factor: intravenous powder for solution.

Serious side effects

Along with its needed effects, antihemophilic factor/von willebrand factor may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking antihemophilic factor/von willebrand factor:

More common side effects

• difficulty with breathing or swallowing
• dizziness
• fast heartbeat
• fever
• hives or welts, itching, rash
• nausea
• reddening of the skin, especially around the ears
• swelling of the face, throat, or tongue
• unusual tiredness or weakness

Incidence not known

• abdominal or stomach pain
• blurred vision
• cough
• headache
• nervousness
• pounding in the ears
• slow or fast heartbeat
• tightness in the chest
• vomiting

For healthcare professionals

Applies to antihemophilic factor/von willebrand factor: intravenous powder for injection.

General adverse events

The most serious side effects were anaphylaxis/hypersensitivity reactions.^[Ref]

Immunologic

• Common (1% to 10%): Allergy, infection, hypersensitivity
• Uncommon (0.1% to 1%): Factor VIII inhibition
• Very rare (less than 0.01%): Von Willebrand factor inhibition, anaphylactic shock
• Frequency not reported: Allergic-anaphylactic reactions, sepsis^[Ref]

Other

• Very common (10% or more): Pain (up to 17.5%)
• Common (1% to 10%): Fever, surgery, facial edema, chest pain, peripheral edema, rigors
• Frequency not reported: Chills, pseudothrombocytopenia, postoperative pain
• Postmarketing reports: Fatigue, malaise^[Ref]

Gastrointestinal

• Very common (10% or more): Nausea (up to 23.8%), constipation (11.1%)
• Common (1% to 10%): Gastrointestinal bleeding, abdominal pain, vomiting
• Frequency not reported: Postoperative nausea^[Ref]

Hematologic

• Common (1% to 10%): Groin bleed, ear bleed, shoulder bleed, anemia/hemoglobin decreased, thromboembolic event
• Frequency not reported: Hemorrhage, hematocrit decreased, postoperative hemorrhage, postoperative wound bleeding
• Postmarketing reports: Hemolysis^[Ref]

Nervous system

• Common (1% to 10%): Cerebral hemorrhage/subdural hematoma, dizziness, headache, dysgeusia, somnolence
• Frequency not reported: Headache, paresthesia, drowsiness^[Ref]

Respiratory

• Common (1% to 10%): Epistaxis, hemoptysis, pulmonary embolus, sore throat
• Frequency not reported: Respiratory distress
• Postmarketing reports: Dyspnea, cough, sneezing, throat irritation^[Ref]

Dermatologic

• Common (1% to 10%): Sweating increased, pruritus, rash, urticaria^[Ref]

Genitourinary

• Common (1% to 10%): Menorrhagia, hematuria, urinary retention, urinary tract infection^[Ref]

Hepatic

• Common (1% to 10%): ALT increased, liver function test abnormal^[Ref]

Musculoskeletal

• Common (1% to 10%): Back pain, muscle and joint stiffness
• Frequency not reported: Extremity pain
• Postmarketing reports: Joint pain^[Ref]

Cardiovascular

• Common (1% to 10%): Thrombophlebitis
• Frequency not reported: Orthostatic hypotension, phlebitis, vasodilation, bradycardia, palpitations^[Ref]

Local

• Common (1% to 10%): Infusion site erythema or rash or pain
• Frequency not reported: Injection site bleeding
• Postmarketing reports: Infusion site pain^[Ref]

Psychiatric

• Common (1% to 10%): Insomnia^[Ref]

Ocular

• Frequency not reported: Blurred vision^[Ref]

Renal

• Frequency not reported: Pyelonephritis^[Ref]

Metabolic

• Postmarketing reports: Hypervolemia^[Ref]

Further information

Dried Factor VIII Fraction Type 8Y side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer