Cyklokapron Side Effects

Generic name: tranexamic acid

Medically reviewed by Drugs.com. Last updated on Dec 19, 2023.

Note: This document contains side effect information about tranexamic acid. Some dosage forms listed on this page may not apply to the brand name Cyklokapron.

Applies to tranexamic acid: intravenous solution. Other dosage forms:

• oral tablet

Serious side effects of Cyklokapron

Along with its needed effects, tranexamic acid (the active ingredient contained in Cyklokapron) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking tranexamic acid:

Incidence not known

• Anxiety
• bloody or cloudy urine
• blurred or loss of vision
• changes in vision
• chest pain or tightness
• confusion
• cough
• difficult or painful urination
• difficulty swallowing
• disturbed color perception
• dizziness, fainting, or lightheadedness when getting up suddenly from a lying or sitting position
• double vision
• fast heartbeat
• halos around lights
• hives, itching, skin rash
• migraine headache
• night blindness
• numbness of the hands
• overbright appearance of lights
• pain, redness, or swelling in the arm or leg
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• redness of the skin
• seizures
• sudden decrease in the amount of urine
• sweating
• trouble breathing
• tunnel vision
• unusual tiredness or weakness

Other side effects of Cyklokapron

Some side effects of tranexamic acid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at injection site
• diarrhea
• giddiness
• nausea
• vomiting

For Healthcare Professionals

Applies to tranexamic acid: compounding powder, intravenous solution, oral tablet.

Cardiovascular

Frequency not reported: Hypotension

Postmarketing reports: Thromboembolic events^[Ref]

Gastrointestinal

Very common (10% or more): Abdominal pain (over 30%)

Common (1% to 10%): Nausea, vomiting, diarrhea^[Ref]

Hypersensitivity

Uncommon (0.1% to 1%): Allergic dermatitis

Postmarketing reports: Anaphylactic shock, allergic skin reactions^[Ref]

Musculoskeletal

Very common (10% or more): Back pain, musculoskeletal pain

Common (1% to 10%): Arthralgia, muscle cramps^[Ref]

Hypersensitivity

A case of severe allergic reaction to tranexamic acid (the active ingredient contained in Cyklokapron) was reported involving a subject on her fourth cycle of treatment who experienced dyspnea, tightening of her throat, and facial flushing that required emergency medical treatment.^[Ref]

Nervous system

Very common (10% or more): Headache, migraine

Frequency not reported: Seizures

Postmarketing reports: Dizziness, seizures^[Ref]

Ocular

Rare (less than 0.1%): Retinal artery occlusion

Postmarketing reports: Chromatopsia, visual impairment^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer