Study Looks at Impact of Peritoneal Dialysis on Thyroid Function
MONDAY, Sept. 23, 2024 -- Patients undergoing peritoneal dialysis (PD) have significantly higher thyroxine (T4) concentrations than hemodialysis (HD) patients and higher free T4 (FT4) concentrations at 12 and 24 months, according to a study published online Sept. 7 in Seminars in Dialysis.
Jelić Pranjić Ita, M.D., from the University Hospital Center Rijeka in Croatia, and colleagues conducted a prospective single-center study to examine thyroid function in 18 PD patients during a 24-month period. Data were compared to those from concurrently treated HD patients.
The researchers found that some of the PD patients had elevated thyroid-stimulating hormone levels initially, which normalized during follow-up, despite longer duration of dialysis. PD patients had significantly higher T4 concentrations at baseline and higher FT4 concentrations at 12 and 24 months compared with HD patients. At baseline and at 12 and 24 months, free triiodothyronine (FT3) levels were significantly higher; after the beginning of the study, T3 levels were within the reference interval. In PD patients, there was a positive association between T4 levels and 24-hour diuresis after 12 months.
"PD's continuous nature offers the benefit of better preservation of residual kidney function and gradual toxin removal," the authors write. "However, the complete precise factors influencing potential differences in survival have not been fully elucidated."
Abstract/Full Text (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Read this next
Evidence Insufficient to Determine Benefits of Multicancer Screening Tests
THURSDAY, Sept. 18, 2025 -- No controlled studies report benefits of screening with multicancer detection (MCD) tests, according to a study published online Sept. 16 in the Annals...
Nonadherence to Cervical Cancer Screening Increased After COVID-19 Pandemic
THURSDAY, Sept. 18, 2025 -- Nonadherence to cervical cancer screening in the United States increased after the COVID-19 pandemic, according to a study published online Sept. 10...
Guidance Issued for Creation of pAVFs for Hemodialysis Access
THURSDAY, Sept. 18, 2025 -- In a guidance document issued by the Society of Interventional Radiology Practice and published online Sept. 9 in the Journal of Vascular and...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.