Dementia Diagnoses Up in Individuals With Acute Kidney Injury
By Elana Gotkine HealthDay Reporter
THURSDAY, Sept. 5, 2024 -- Individuals with acute kidney injury (AKI) have an increased risk for receiving a clinical diagnosis of dementia, according to a study published online Aug. 22 in Neurology.
Hong Xu, M.D., Ph.D., from the Karolinska Institutet in Stockholm, and colleagues examined the association between experiencing AKI and subsequent risks for developing dementia in a study involving individuals aged 65 years and older in Stockholm, who were free from dementia diagnosis. A total of 305,122 individuals (median age, 75 ± 8 years) were included.
The researchers found that 79,888 individuals (26 percent) were suffering from a least one episode of AKI during a median follow-up of 12.3 years and there were 47,938 (16 percent) incident dementia cases. The rate of dementia cases was 37.0 per 1,000 person-years after AKI compared with 17.3 during the period before AKI. Developing AKI was associated with a significantly increased rate of subsequent dementia after multivariable adjustment (adjusted hazard ratio, 1.49). Across dementia types, this pattern was consistent, with hazard ratios of 1.88, 1.47, and 1.31 for dementia with Lewy bodies and Parkinson disease with dementia, vascular dementia, and Alzheimer dementia, respectively. Across more severe AKIs and in hospital-acquired versus community-acquired AKI, risk associations were stronger in magnitude.
"As a clinical application, this study thus identifies individuals with AKI as a population in which monitoring for dementia and potential preventive and therapeutic strategies may be indicated," the authors write.
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted September 2024
Read this next
Gabapentin for Back Pain Linked to Increased Risk for Dementia, MCI
FRIDAY, July 11, 2025 -- For adults with chronic low back pain, gabapentin prescription is associated with an increased risk for dementia and mild cognitive impairment (MCI)...
Lead Exposure Linked to Faster Rate of Forgetting Among Children
FRIDAY, July 11, 2025 -- Developmental lead (Pb) exposure is associated with an increased rate of forgetting among children, according to a study published online July 9 in...
Exposure to Trihalomethanes Linked to Chronic Kidney Disease
TUESDAY, July 8, 2025 -- Exposure to trihalomethanes, especially brominated trihalomethanes, in residential community water supplies (CWS) is associated with an increased risk for...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.