Automated Multiorgan CT Can Predict Diabetes, Other Conditions
By Elana Gotkine HealthDay Reporter
FRIDAY, Aug. 16, 2024 -- Automated multiorgan computed tomography (CT), including visceral fat, can predict diabetes and associated cardiometabolic conditions, according to a study published online Aug. 6 in Radiology.
Yoosoo Chang, M.D., Ph.D., from Sungkyunkwan University School of Medicine in Seoul, South Korea, and colleagues examined the ability of automated CT-derived markers to predict diabetes and associated cardiometabolic comorbidities in a retrospective cohort study of Korean adults. Participants underwent health screening with fluorine 18 fluorodeoxyglucose positron emission tomography/CT between January 2012 and December 2015. Data were included for 32,166 adults in a cross-sectional analysis and for 27,298 adults in a cohort analysis.
The researchers found that diabetes prevalence and incidence were 6 and 9 percent at baseline and during the 7.3-year median follow-up, respectively. The highest predictive performance for prevalent and incident diabetes was seen for the visceral fat index, with areas under the curve (AUCs) of 0.70 and 0.82 for men and women, respectively, and C-indexes of 0.68 and 0.82, respectively. Predictive performance was improved by combining visceral fat, muscle area, liver fat faction, and aortic calcification, yielding C-indexes of 0.69 and 0.83 for men and women, respectively. For identifying metabolic syndrome, the AUCs for the visceral fat index were 0.81 and 0.90 for men and women, respectively. Ultrasound-diagnosed fatty liver, coronary artery calcium scores >100, sarcopenia, and osteoporosis were also identified by CT-derived markers, with AUCs ranging from 0.80 to 0.95.
"CT-derived parameters, particularly the visceral fat area index, outperformed traditional methods for predicting type 2 diabetes mellitus in both sexes," the authors write.
Several authors disclosed ties to MEDICAL IP.
Editorial (subscription or payment may be required)
Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.
© 2025 HealthDay. All rights reserved.
Posted August 2024
Read this next
Risk for Death From Prostate Cancer Low With Guideline Care for Nonmetastatic Disease
MONDAY, July 14, 2025 -- Men with nonmetastatic prostate cancer receiving guideline-concordant care have a much higher risk for death from causes other than prostate cancer...
AI Support Improves Breast Cancer Detection Accuracy in Mammography
MONDAY, July 14, 2025 -- Artificial intelligence (AI) support improves radiologists' breast cancer detection accuracy when reading mammograms, according to a study published...
Consistent Physical Activity Linked to Reduced All-Cause, CVD Mortality
FRIDAY, July 11, 2025 -- Consistently and increasingly accumulated physical activity (PA) is associated with a reduced risk for all-cause and cardiovascular disease (CVD)...
More news resources
- FDA Medwatch Drug Alerts
- Daily MedNews
- News for Health Professionals
- New Drug Approvals
- New Drug Applications
- Drug Shortages
- Clinical Trial Results
- Generic Drug Approvals
Subscribe to our newsletter
Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.