Can you use adapalene and Duobrii together?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on Aug 1, 2024.

Official Answer by Drugs.com

Adapalene and Duobrii (halobetasol and tazarotene) can be used together, since they are FDA approved for different skin conditions.

Adapalene is a topical retinoid that may be used to treat acne.
Duobrii is a combination of a topical steroid and retinoid that may be used to treat psoriasis.

Applying both medications to the same area of skin can lead to more side effects, since both contain a retinoid. These side effects usually occur at the application site, and may include:

Pain
Redness
Scaling
Dryness
Itching
Burning or stinging

If you need to apply both medications on the same area of skin, ask your dermatologist or other healthcare provider if you can space out the dosing to avoid side effects. For example, you may be able to apply one medication in the morning and the other at night.

Follow up with your doctor or other healthcare provider if you have questions about using multiple skin products at the same time.

References

Duobrii [package insert]. Updated January 2020. Bausch Health US, LLC. Accessed August 1, 2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b3f0cdc0-69fd-43d1-baf2-d776a3a20715

Adapalene cream [package insert]. Updated August 2021. E. Fougera & Co. a division of Fougera Pharmaceuticals Inc. Accessed August 1, 2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=276f7cce-5f54-40f8-8321-9192d0e52a73

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Can you use adapalene and Duobrii together?

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