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Does Wegovy make you pee a lot or urine smell?

Medically reviewed by Carmen Pope, BPharm. Last updated on Sep 12, 2023.

Official answer

by Drugs.com

Some people have reported a change in the way their urine smells after taking Wegovy or other semaglutide products such as Ozempic, often describing it as now having a strong unusual odor.

The main way Wegovy is excreted from the body is via the urine and faces and 3% of the dose is left unchanged, which may alter the composition of the urine and change its smell.

Healthcare providers recommend you increase your water intake while taking Wegovy and this could result in your peeing more.

Other smell-related changes include an increase in sulfur-smelling burps or burps with a strong odor. There may be two reasons for this:

  • Wegovy slows your digestive system down so it takes longer for food and waste to travel through your body which can increase how much water is pulled out of the food, and increase the amount of decomposition and constipation– making it smell more.
  • Wegovy may increase the number of sulfur-producing bacteria in your gut.
References
  • Wegovy product Information. https://www.novo-pi.com/wegovy.pdf
  • Beware the Ozempic Burp. The Atlantic. May 2, 2023. https://www.theatlantic.com/health/archive/2023/05/ozempic-burping-smell-eggs-side-effect/673925/

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