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Can I drink alcohol on Ozempic?

Medically reviewed by Carmen Pope, BPharm. Last updated on Jan 30, 2025.

Official answer

by Drugs.com

If you are wanting to drink alcohol while you are taking Ozempic (semaglutide), you need to think about several important health risks. Drinking alcohol on Ozempic can significantly impact blood sugar levels and may reduce the effectiveness of Ozempic.

Key Risks of Mixing Ozempic and Alcohol

Blood Sugar Fluctuations

The combination of Ozempic and alcohol can create unpredictable changes in blood glucose levels. This occurs because:

  • Alcohol interferes with your liver's normal blood sugar regulation
  • Ozempic's blood sugar-lowering effects may become enhanced
  • The risk of hypoglycemia (dangerously low blood sugar) increases
  • Blood sugar responses become harder to predict and manage.

Enhanced Effects of Alcohol

Ozempic can alter how your body processes alcohol in several ways:

  • Alcohol's effects on blood sugar become more pronounced
  • The speed of alcohol's impact on your system may increase
  • Your usual tolerance to alcohol might change
  • The risk of alcohol-related complications may be higher.

Long-term Concerns

Regular alcohol consumption while taking Ozempic can lead to several problems:

  • Decreased medication effectiveness over time
  • Potential development of medication tolerance
  • Compromised diabetes management
  • Increased risk of diabetes-related complications.

Related questions

Managing Risk and Safety

Recommendations for Patients

If you choose to consume alcohol while taking Ozempic:

  • Always consult with your healthcare provider first
  • Monitor blood sugar levels more frequently
  • Start with smaller amounts of alcohol to gauge your response
  • Never drink on an empty stomach
  • Keep glucose tablets or quick-acting carbohydrates available

Warning Signs to Watch

Seek immediate medical attention if you experience:

  • Severe dizziness or confusion
  • Unusual sweating or shakiness
  • Extreme fatigue
  • Difficulty maintaining blood sugar levels
  • Persistent nausea or vomiting.

Important Considerations for Healthcare Providers

Healthcare professionals should:

  • Assess patient's alcohol consumption patterns
  • Adjust monitoring protocols for patients who drink alcohol
  • Consider alternative medications if necessary
  • Provide clear guidance on safe alcohol consumption.

Related: Do semaglutide or liraglutide work for alcohol use disorder?

References

Read next

Why am I not losing weight on Ozempic?

Although Ozempic is not FDA-approved for weight loss, over 86% of people lose at least 5% of their body weight in trials that have studied semaglutide, the active ingredient of Ozempic. But the same clinical trials also show that just under 14% don’t lose weight, and some may even gain weight. Continue reading

How does semaglutide work for weight loss?

You could lose weight with semaglutide (Wegovy) because you will eat less, and feel fuller when you do eat. Semaglutide does this by closely mimicking a natural hormone in our bodies called incretin. It targets an area in the brain (called GLP-1 receptors) that help to regulate your appetite and how much you eat and works over the longer term. Continue reading

Where and how should Ozempic be injected?

Ozempic (generic name: semaglutide) is a pen prefilled with an injectable medicine given by self-injection once a week, on the same day each week, with or without meals. Ozempic is injected under the skin (subcutaneously) in your stomach (abdomen), thigh, or upper arm area. Continue reading

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