How long should you take Xgeva for?
Xgeva is meant to be taken long-term. However, Xgeva should be discontinued if you experience intolerable side effects or serious side effects such as osteonecrosis of the jaw or osteomyelitis, or if Xgeva appears to be ineffective for you.
There have been reports of a higher risk of multiple vertebral fractures and hypercalcemia (high calcium levels) occurring within the first year following discontinuation of Xgeva. Patients should be monitored for both conditions when Xgeva is stopped.
Common side effects reported with Xgeva are bone and joint pain, diarrhea, headache, low phosphate levels, nausea, shortness of breath, and tiredness. Common serious adverse reactions include osteonecrosis of the jaw and osteomyelitis. Always tell your doctor if you experience any new or unusual thigh, hip or groin pain; bone, joint, or muscle pain; or jaw pain.
References
- Xgeva (denosumab) [Package Insert] 02/2020 Amgen Inc https://www.drugs.com/pro/xgeva.html
Read next
Xgeva vs Prolia. How do they compare?
Xgeva and Prolia are both brand names for the generic drug denosumab. Both are injectable preparations, both are made by Amgen, and both have similar side effects; but they differ in their indications, the way they are given, and their dosage. Continue reading
Is Xgeva a chemotherapy drug?
Xgeva is not a chemotherapy drug, it is a targeted treatment, called a monoclonal antibody that modifies bone. Although it is not a chemotherapy drug it is often given with chemotherapy medicines. Continue reading
Does Xgeva cause bone pain?
Xgeva may cause pain in the bones, muscles, and joints. Xgeva may also rarely cause osteonecrosis of the jaw, a bone condition with symptoms such as jaw pain or persistent mouth pain. Conversely, Xgeva is more effective than zoledronic acid at extended the bone pain-free interval. Always report new or unusual thigh, hip, groin, bone, joint, muscle, or jaw pain to your doctor. Continue reading
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