Xgeva User Reviews & Ratings

• Jef...
• Taken for 1 to 6 months
• February 8, 2020

For Osteolytic Bone Metastases of Solid Tumors "I just had my third dose of Xgeva, I have them monthly for metastatic breast cancer. The first two times I had some lower back pain and minor aches and just feeling yucky for 24 hours. I had my third shot yesterday. I woke up after midnight in a lot of pain. My bones, muscles, and joints hurt. I was able to fall back to sleep but felt awful the next day and had more localized pain where my cancer is. When I related this to my doctor's nurse, she was surprised because she had never heard of this. I've read quite a few reviews of other patients experiencing the same thing. I'm uncertain as to continue taking this medication."

• AW ...
• December 17, 2016

For Hypercalcemia of Malignancy "I have lung cancer with mets to bone. Two hours after the injection, I experienced the worst pain ever in my life! I walked into the infusion area without any body pain, just a very slight backache which Advil was helping, and 2 hours later I was crippled. It's 2 weeks now, and I'm either in a wheelchair or walking around the house with a cane. Horrible, horrible medication. I now take oxycontin every 12 hours and oxycodone every 3 hours. Refuse this drug if you are smart. Even my oncologist is 'surprised' with the side effects I have. I refuse to have a second injection of Xgeva."

• Kim...
• Taken for 2 to 5 years
• June 8, 2019

For Osteolytic Bone Metastases of Solid Tumors "I have been on Xgeva for the last three years, I have breast cancer stage 3. I receive the shots every 3 months, and I take a calcium pill every day. I don’t have pain from the Xgeva. I only get a burning sensation with the shot. If I feel cramping in my legs, I eat a banana every day. I don’t know how long it is effective. Does anyone else know how many years or how long you can take it or how long it is effective for?"

• Unl...
• Taken for 6 months to 1 year
• November 16, 2019

For Osteolytic Bone Metastases of Solid Tumors "I had been having injections of Xgeva for 7 months; I never had any difficulty - after my eighth injection, after two days, I developed horrific pains at the sites of very old bone and joint injuries - I cannot explain why the difference - even my hands hurt! I am very reluctant to take any more of this drug."

• TKa...
• Taken for 2 to 5 years
• October 19, 2019

For Giant Cell Tumor of Bone "Took Xgeva for 2 years for Giant Cell Tumor of the spine. Doctor stopped it after 2 years because I was doing so well. Exactly six months later, the tumor came back. Now I'm on another round of treatments."

• Mug...
• Taken for 1 to 2 years
• August 12, 2021

For Osteolytic Bone Metastases of Solid Tumors "I have prostate cancer that metastasized to the bone. This would be stage 4 prostate cancer. The prostate was removed by surgery 10 years earlier. I have been getting Xgeva injections for about 14 months. The pain I notice is in both upper legs and my low back. Pain could be from cancer or Xgeva. Just don't know. The back hurts a lot. I have learned to pre-medicate with Aleve or Tylenol about 2 hours before going to bed. This usually works. I go to bed without pain, but it comes on as I lay in bed, so I catch it early."

• Anonymous
• Taken for 1 to 2 years
• March 23, 2024

For Osteolytic Bone Metastases of Solid Tumors "I have been taking Xgeva for 1 1/2 years and the metastasis on my back has greatly improved with no side effects. I am taking vitamins C, D3, and Calcium. My oncologist and I are very satisfied so far. Thanks."

• Ano...
• Taken for less than 1 month
• July 10, 2025

For Hypercalcemia of Malignancy "During routine monitoring by the oncologist, moderate hypercalcemia was noted (no known active bone mets). The doctor proposed a quick injection to correct it, failing to explain that it is a monoclonal antibody product (Xgeva), as I would never have consented to it. I strongly encourage everyone to read the composition of the medication and side effects list before accepting to be injected. Seventy-two hours after the injection, I was feeling as if I was going to die: general malaise, nausea, weakness to the point of inability to move. This prompted an ER visit. Strangely enough, apart from a sudden drop in phosphorus by 60% in 4 days, the blood test revealed no major issues. I still continue to feel dreadful, though getting a bit better 10 days after the injection. Doctors did not give me any answers…"

• Anonymous
• March 23, 2024

For Osteolytic Bone Metastases of Solid Tumors "I have been taking Xgeva for 1 1/2 years and the metastasis on my back has greatly improved with no side effects. I am taking vitamins C, D3, and Calcium. My oncologist and I are very satisfied so far. Thanks."

• Wee...
• June 20, 2018

For Osteolytic Bone Metastases of Solid Tumors "Terrible side effects: bone pain, weakness, groin, and hip pain."