How long does it take Ilumya to work?
It takes approximately 12 weeks for Ilumya (tildrakizumab) to start working with nearly 60% of people experiencing a 75% reduction in the severity of their psoriasis within that time; however, it may take over a year for the full benefits to be seen.
Research has shown that after 12 weeks:
- 55% to 58% of people administered Ilumya had cleared or minimal disease according to their PGA (physicians global assessment) score compared to 4% to 7% of those administered placebo
- 61% to 64% had experienced a 75% reduction in their disease as defined by their PASI score
- 35% to 39% had experienced a 90% reduction in their disease as defined by their PASI score
- 12% to 14% had experienced a 100% reduction in their disease as defined by their PASI score.
Longer-term studies have indicated the percentage of people experiencing benefit increases with continued treatment.
- After 28 weeks of treatment, 74% of people administered Ilumya had experienced a 75% reduction in their disease as defined by their PASI score
- After 64 weeks of treatment, 84% of people administered Ilumya had experienced a 75% reduction in their disease as defined by their PASI score.
Some people who previously been assigned Ilumya in the trial were then given a placebo. It took an average of 20 weeks for the benefits of Ilumya to be lost once it had been discontinued.
References
- Ilumya (tildrakizumab-asmn) 07/2020 Sun Pharmaceutical Industries, Inc. https://www.drugs.com/pro/ilumya-injection.html
- Tang C, Chen S, Qian H, Huang W. Interleukin-23: as a drug target for autoimmune inflammatory diseases. Immunology. 2012;135(2):112-124. DOI:10.1111/j.1365-2567.2011.03522.x
- Targeting Psoriasis at IL-23 SunPharma 2020 https://www.ilumyapro.com/ilumya-mechanism-of-action/
Read next
Related medical questions
- How does Ilumya affect my immune system?
- How does Ilumya work to treat psoriasis?
- What are the side effects of Ilumya?
- How is Ilumya administered?
- What are the new drugs for plaque psoriasis?
- How does Tremfya work to treat plaque and psoriatic arthritis?
- Where should you not use triamcinolone acetonide cream?
- Halobetasol vs. clobetasol - How do they compare?
- Does taking vitamin D help with psoriasis?
- What causes Plaque Psoriasis?
- Sotyktu vs Otezla: How do they compare?
- How long does it take for Otezla to work?
- How do you inject Humira?
- How to stop taking Otezla?
- What are 6 key Taltz side effects to watch out for?
- Cosentyx vs Humira: How do they compare?
- How long does Cimzia take to work?
- What's the dosing schedule for Skyrizi?
- Who is the actress in the Stelara commercial?
- What happens if Cosentyx is not refrigerated?
- How long does Cosentyx take to work?
- Can Enstilar be used on the scalp?
- How long does it take for Sotyktu to work?
- What is the mechanism of action of infliximab?
- Who makes Otezla and why is it so expensive?
- Is Otezla (apremilast) an immunosuppressant?
- Does Cosentyx cause weight gain or loss?
- Does Skyrizi cause cancer?
- Does Otezla cause weight gain?
- Can you drink alcohol while taking Skyrizi?
Drug information
Related support groups
- Ilumya (9 questions, 3 members)
- Tildrakizumab (6 questions, 3 members)
- Plaque Psoriasis (84 questions, 69 members)