Can Kyleena cause weight gain?
Yes, Kyleena can cause weight gain in some women although this is not listed as a common side effect of Kyleena. Weight gain associated with Kyleena is most likely due to water retention caused by the progestin contained in Kyleena, rather than an increase in body fat percentage. In most women, the bloating should subside within a few months.
How does Kyleena cause weight gain?
Kyleena is a T-shaped plastic contraceptive device that is inserted into the uterus and which contains the hormone progestin which is thought to increase plasma volume by causing increased protein retention in the vascular space as well as an overall expansion of extracellular fluid.
This causes fluid retention which in turn can lead to bloating.
How can you treat Kyleena-associated weight gain?
In most women, the bloating caused by Kyleena will subside as a woman’s body gets used to the progestin in the contraceptive device. In addition, women are more likely to gain weight during their reproductive years, whether they have an IUD or not.
Other recent lifestyle changes should also be considered as a factor for weight gain, such as an increase in food intake, a decrease in exercise, stress, or other medications. All women should ensure they eat a healthy balanced diet, partake in regular exercise, and stay hydrated with lots of water.
If the weight gain is significant or worrisome and lifestyle changes have not made a difference, then contact your doctor for further advice.
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What are the most common side effects with Kyleena?
The most common side effects reported in clinical trials with Kyleena include:
- Vulvovaginitis (irritation and inflammation of the vulva and vaginal area): 24.3%
- Ovarian cysts: 22.2%
- Acne: 14.1%
- Abdominal pain: 13.3%
- Headache: 12.9%
- Pelvic pain: 8.2%
- Dysmenorrhea (pain during menstruation): 8%
- Increased bleeding: 7.9%
- Breast pain: 7.1%
- Nausea: 4.7%
- Genital discharge: 4.5%
- Depression: 4.4%
- Breast discomfort: 3.5%
- Device expulsion: 3.5%
- Migraine: 3.3%
- Uterine spasm: 2.4%
- Seborrhea (excessive discharge of sebum): 1.8%
- Upper genital tract infections: 1.5%
- Alopecia: 1%
Serious adverse events that occur in less than 1% of people include ectopic pregnancy, pelvic inflammatory disease, spontaneous abortion, and uterine perforation.
References
- Kyleena 02/2020 Bayer HealthCare Pharmaceuticals Inc. https://www.drugs.com/pro/kyleena.html
- Kyleena. https://www.kyleena-us.com/
- Stachenfeld NS. Sex hormone effects on body fluid regulation. Exerc Sport Sci Rev. 2008;36(3):152-159. DOI:10.1097/JES.0b013e31817be928
Read next
Can Kyleena make your period stop?
Yes, Kyleena may make your period stop. Research has shown that 12 out of 100 women (12%) or women stop having periods after one year of Kyleena use. Typically, most women experience some sort of change in their periods, usually during the first three to six months after Kyleena insertion. Their periods may become lighter or more irregular or spotting may occur in between periods. Some women experience heavy bleeding during this time. However, these changes usually settle down after about 6 months with most women experiencing shorter and lighter periods once their body adjusts. Continue reading
How long does it take for Kyleena to work?
Kyleena is immediately effective if inserted within the first 7 days of a woman’s period, immediately following a first-trimester abortion or miscarriage, or if inserted the same day as a hormonal contraceptive implant or intrauterine device is removed. In other circumstances, it may take up to seven days for Kyleena to become effective and another method of contraception should be used or the woman should abstain from vaginal intercourse for 7 days to prevent pregnancy. Continue reading
How long does Kyleena last?
Kyleena will last for up to five years and is over 99% effective at preventing pregnancy for this time. Continue reading
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Drug information
- Kyleena Information for Consumers
- Kyleena prescribing info & package insert (for Health Professionals)
- Side Effects of Kyleena (detailed)
- Kyleena user reviews (1,631)
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