Skip to main content

How many puffs are in Breztri Aerosphere inhaler?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on March 31, 2025.

Official answer

by Drugs.com

Breztri Aerosphere comes in two inhaler sizes:

  • 120 inhalations per canister
  • 28 inhalations per canister

Each inhaler has a built-in dose counter that tracks the remaining puffs. The pointer in the dose indicator display moves after each use, counting down by one.

  • When the pointer enters the yellow zone, it means the inhaler is running low, and you should order a refill.
  • When the pointer reaches zero in the red zone, the inhaler should be discarded.
  • The 120-puff inhaler should be discarded 3 months after being removed from its foil pouch.
  • The 28-puff inhaler should be discarded 3 weeks after opening.

What Is Breztri Aerosphere?

Breztri Aerosphere (budesonide, glycopyrrolate, and formoterol) is a prescription aerosol inhaler used for the maintenance treatment of chronic obstructive pulmonary disease (COPD) in adults. It contains three active ingredients:

  • Budesonide – A corticosteroid that reduces inflammation.
  • Glycopyrrolate – A long-acting muscarinic antagonist (LAMA) that helps relax airway muscles.
  • Formoterol fumarate – A long-acting beta agonist (LABA) that improves airflow.

Each inhalation delivers:

  • 160 mcg of budesonide
  • 9 mcg of glycopyrrolate
  • 4.8 mcg of formoterol fumarate

Related questions

Important Notes:

Breztri Aerosphere is not used to treat sudden breathing symptoms of COPD. Make sure to have a rescue inhaler (a short-acting bronchodilator like albuterol) with you at all times to treat sudden symptoms. Contact your healthcare provider if your breathing symptoms are worsening during your treatment with Breztri Aerosphere or if you do not have a rescue inhaler.

How long does Breztri Aerosphere inhaler last?

The duration of your Breztri Aerosphere inhaler depends on its size and dosage regimen.

  • 120-inhalation canister: Lasts about 1 month when used as prescribed (2 puffs twice daily).
  • 28-inhalation canister: Lasts about 1 week when used as prescribed.

Even if you still have medication inside your inhaler, remember to throw it away after it has been 3 months for the 120-puff inhaler or 3 weeks for the 28-day inhaler since removing it from the foil pouch.

This is not all the information you need to know about Breztri Aerosphere for safe and effective use. Review the full Breztri Aerosphere information, and discuss this and any questions you have with your doctor or other health care provider.

References

Breztri Aerosphere [package insert]. Updated January 2022. AstraZeneca Pharmaceuticals LP. Accessed September 11, 2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=715433dc-cb2b-43ea-b6df-c5b4177adc6c

Read next

What is the normal oxygen level for someone with COPD?

Between 88% and 92% oxygen level is considered safe for someone with moderate to severe COPD. Oxygen levels below 88% become dangerous, and you should ring your doctor if it drops below that. If oxygen levels dip to 84% or below, go to the hospital. Any level 80% and lower is dangerous for your vital organs and needs urgent treatment. Continue reading

What is the life expectancy of someone with COPD?

Studies have shown that for a male who is still smoking at age 65 and classified with GOLD Stage 3 or 4 COPD, the life expectancy was reduced by 5.8 years. For a male 65 years of age with Stage 1 disease and still smoking, life expectancy was reduced 0.3 years, and for Stage 2, it was reduced by 2.2 years. In addition, there are another 3.5 years of life lost due to smoking itself. Continue reading

Is Symbicort a steroid inhaler?

Symbicort contains an inhaled corticosteroid (“steroid”) known as budesonide to reduce inflammation in the lungs, but also contains a medicine known as formoterol. Formoterol is a long-acting inhaled bronchodilator that relaxes muscles in the airways to improve breathing. Continue reading

Related medical questions

Drug information

Related support groups