How long does it take for Jaypirca to work?

Jaypirca (pirtobrutinib) begins working soon after you start taking it, but the full effects may take a few months to appear. In clinical studies, some patients experienced tumor shrinkage as early as:

• 7 weeks for chronic lymphocytic leukemia (CLL)
• 3.5 weeks for mantle cell lymphoma (MCL)

Jaypirca for Chronic Lymphocytic Leukemia (CLL)

In a clinical trial of adult patients who had received at least two prior treatments:

• Some patients saw their cancer shrink and stop spreading around 7 weeks after starting treatment.
• The median time for cancer shrinkage and stabilization was 3.7 months.
• The range of response times varied from 1.7 months to 27.9 months.

Jaypirca for Mantle Cell Lymphoma (MCL)

In a clinical trial of adults with MCL who had received at least two prior treatments:

• Some patients saw tumor reduction and disease control as early as 3.5 weeks.
• The median time for cancer shrinkage and stabilization was 1.8 months.
• The range of response times varied from 3.5 weeks to 4.2 months.

How Does Jaypirca Work?

Jaypirca is a BTK inhibitor. BTK is a protein that signals activation of cancerous B-cells to multiply. By blocking BTK, Jaypirca stops cancer cells from multiplying and spreading in the body.

This is not all the information you need to know about Jaypirca (pirtobrutinib) for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider.