How long does it take for Breztri to work?

Breztri Aerosphere (budesonide, glycopyrrolate, and formoterol) begins working within about 5 minutes, improving lung function and easing breathing. However, full effects may take up to 4 weeks, as the corticosteroid component gradually reduces airway inflammation. Daily use is essential for the best results.

Clinical Data on Breztri’s Effectiveness

In clinical studies, patients taking Breztri Aerosphere saw a 100 mL increase from their baseline FEV1 (forced expiratory volume in one second) within around 5 minutes after inhaling a dose on the first day. FEV1 measures how much air you can forcefully exhale in the first second after inhaling. This test is used to help classify the severity of lung disease such as chronic obstructive pulmonary disease (COPD).

Is Breztri Fast-Acting?

Yes, Breztri Aerosphere works quickly (within 5 minutes) to improve lung function in people with COPD. This is due to two ingredients in Breztri:

• formoterol (a long-acting beta agonist, or LABA), and
• glycopyrrolate (an anticholinergic).

When inhaled, these medications reach the lungs rapidly and start to work within minutes to open up the airways. The third ingredient in Breztri Aerosphere, budesonide, is a steroid and works more slowly.

Breztri Aerosphere should not be used to treat a sudden breathing attack. Make sure you always have a rescue inhaler, such as albuterol, in case of sudden breathing problems.

This is not all the information you need to know about Breztri Aerosphere for safe and effective use. Review the full Breztri Aerosphere information, and discuss this and any questions you have with your doctor or other health care provider.