Drug Interactions between Symproic and trazodone
This report displays the potential drug interactions for the following 2 drugs:
- Symproic (naldemedine)
- trazodone
Interactions between your drugs
No interactions were found between Symproic and trazodone. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Symproic
A total of 168 drugs are known to interact with Symproic.
- Symproic is in the drug class peripheral opioid receptor antagonists.
- Symproic is used to treat Opioid-Induced Constipation.
trazodone
A total of 650 drugs are known to interact with trazodone.
- Trazodone is in the drug class phenylpiperazine antidepressants.
-
Trazodone is used to treat the following conditions:
- Anxiety (off-label)
- Depression
- Fibromyalgia (off-label)
- Headache (off-label)
- Insomnia (off-label)
- Major Depressive Disorder
- Reflex Sympathetic Dystrophy Syndrome (off-label)
- Sedation
Drug and food interactions
traZODone food
Applies to: trazodone
Alcohol can increase the nervous system side effects of traZODone such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with traZODone. Do not use more than the recommended dose of traZODone, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
naldemedine food
Applies to: Symproic (naldemedine)
Grapefruit juice can increase the blood levels of naldemedine. This may increase side effects and withdrawal symptoms such as sweating, tearing, runny nose, chills, diarrhea, abdominal pain, anxiety, insomnia, irritability, restlessness, and yawning. You should limit the consumption of grapefruit and grapefruit juice during treatment with naldemedine. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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