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Drug Interactions between Neosporin and tobramycin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

tobramycin neomycin topical

Applies to: tobramycin and Neosporin (bacitracin / neomycin / polymyxin b topical)

GENERALLY AVOID: Topically applied aminoglycosides may be systemically absorbed and have potentially additive effects with systemically administered aminoglycosides. The risk of oto- and nephrotoxicity and other adverse effects of aminoglycosides may be increased.

MANAGEMENT: Topical preparations containing an aminoglycoside should not be used with other aminoglycosides in circumstances where significant systemic absorption could occur (e.g., application to burnt or broken skin; use of large quantities or on large areas for prolonged periods). The normally recommended dosages of these products should not be exceeded.

References (1)
  1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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