Lithium Drug Interactions
Currently displaying a list of 718 drugs known to interact with lithium.
- 184 major drug interactions
- 497 moderate drug interactions
- 37 minor drug interactions
Medications known to interact with lithium
Note: Showing generic names only.
5
A
- abarelix
- abiraterone
- acarbose
- acebutolol
- acetazolamide
- acetohexamide
- acetylcarbromal
- acrivastine
- acyclovir
- adagrasib
- adefovir
- adenosine
- albiglutide
- albuterol
- alfentanil
- alfuzosin
- allopurinol
- almotriptan
- alogliptin
- alprazolam
- amifampridine
- amiloride
- aminophylline
- amiodarone
- amisulpride
- amitriptyline
- amlodipine
- amobarbital
- amoxapine
- amphetamine
- amyl nitrite
- anagrelide
- apalutamide
- apomorphine
- apraclonidine ophthalmic
- aprocitentan
- arformoterol
- aripiprazole
- arsenic trioxide
- asciminib
- asenapine
- aspirin
- astemizole
- atenolol
- atomoxetine
- atracurium
- azatadine
- azelastine nasal
- azilsartan medoxomil
- azithromycin
B
- baclofen
- balsalazide
- bedaquiline
- benazepril
- bendroflumethiazide
- benzphetamine
- benzthiazide
- benztropine
- bepridil
- betaxolol
- bexagliflozin
- bicalutamide
- bisoprolol
- bitolterol
- botulism immune globulin
- brexanolone
- brexpiprazole
- brigatinib
- brimonidine ophthalmic
- brimonidine topical
- brivaracetam
- bromfenac
- bromocriptine
- brompheniramine
- bumetanide
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cabozantinib
- caffeine
- calcitonin
- canagliflozin
- candesartan
- cannabidiol
- cannabis
- captopril
- carbamazepine
- carbetapentane
- carbinoxamine
- cariprazine
- carisoprodol
- carvedilol
- celecoxib
- cenobamate
- ceritinib
- cetirizine
- chlophedianol
- chloral hydrate
- chlordiazepoxide
- chlormezanone
- chloroquine
- chlorothiazide
- chlorphenesin
- chlorpheniramine
- chlorpromazine
- chlorpropamide
- chlorthalidone
- chlorzoxazone
- choline salicylate
- cidofovir
- cilostazol
- ciprofloxacin
- cisapride
- cisatracurium
- cisplatin
- citalopram
- clarithromycin
- clemastine
- clevidipine
- clobazam
- clofarabine
- clofazimine
- clomipramine
- clonazepam
- clonidine
- clorazepate
- clozapine
- codeine
- colesevelam
- crizotinib
- cyclizine
- cyclobenzaprine
- cyproheptadine
- cytomegalovirus immune globulin
D
- dantrolene
- dapagliflozin
- daridorexant
- darolutamide
- dasatinib
- daunorubicin
- daunorubicin liposomal
- deferasirox
- degarelix
- demeclocycline
- desipramine
- desvenlafaxine
- deutetrabenazine
- dexbrompheniramine
- dexfenfluramine
- dexmedetomidine
- dextroamphetamine
- dextromethorphan
- dezocine
- diatrizoate
- diazepam
- diazoxide
- diclofenac
- diclofenac topical
- difelikefalin
- diflunisal
- diltiazem
- dimenhydrinate
- dimethyl fumarate
- diphenhydramine
- diroximel fumarate
- disopyramide
- divalproex sodium
- dobutamine
- dofetilide
- dolasetron
- donepezil
- doxacurium
- doxazosin
- doxepin
- doxepin topical
- doxorubicin
- doxorubicin liposomal
- doxycycline
- doxylamine
- dronabinol
- dronedarone
- droperidol
- dulaglutide
- duloxetine
E
- efavirenz
- efbemalenograstim alfa
- eflapegrastim
- eletriptan
- empagliflozin
- enalapril
- enalaprilat
- encorafenib
- entacapone
- entecavir
- entrectinib
- enzalutamide
- epinephrine
- epirubicin
- eplerenone
- eprosartan
- eravacycline
- eribulin
- ertugliflozin
- erythromycin
- escitalopram
- esketamine
- eslicarbazepine
- esmolol
- estazolam
- eszopiclone
- ethacrynic acid
- ethanol
- ethchlorvynol
- ethosuximide
- ethotoin
- etidronate
- etodolac
- etrasimod
- evening primrose
- everolimus
- exenatide
- ezogabine
F
- famotidine
- felbamate
- felodipine
- fenfluramine
- fenoprofen
- fentanyl
- fexinidazole
- filgrastim
- fingolimod
- flavoxate
- flecainide
- flibanserin
- fluconazole
- flucytosine
- fluoxetine
- fluphenazine
- flurazepam
- flurbiprofen
- flutamide
- fluvoxamine
- formoterol
- foscarnet
- fosinopril
- fosphenytoin
- fostemsavir
- frovatriptan
- furazolidone
- furosemide
G
- gabapentin
- gabapentin enacarbil
- galantamine
- ganaxolone
- gatifloxacin
- gemifloxacin
- gepirone
- gilteritinib
- ginkgo
- givinostat
- glasdegib
- glimepiride
- glipizide
- glyburide
- glycerol phenylbutyrate
- goserelin
- granisetron
- grepafloxacin
- guanethidine
- guanfacine
H
- halazepam
- halofantrine
- haloperidol
- halothane
- heroin
- histrelin
- hydralazine
- hydrochlorothiazide
- hydrocodone
- hydroflumethiazide
- hydromorphone
- hydroxychloroquine
- hydroxyzine
I
- ibandronate
- ibuprofen
- ibutilide
- idarubicin
- ifosfamide
- iloperidone
- imipramine
- immune globulin intravenous
- immune globulin intravenous and subcutaneous
- indacaterol
- indapamide
- indomethacin
- inotersen
- inotuzumab ozogamicin
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- iodamide
- iodine
- iodipamide
- iodixanol
- ioflupane I 123
- iohexol
- iomeprol
- iopamidol
- iopromide
- iothalamate
- ioversol
- ioxaglate
- ioxilan
- irbesartan
- isocarboxazid
- isoetharine
- isoniazid
- isoproterenol
- isosorbide dinitrate
- isosorbide mononitrate
- isradipine
- ivabradine
- ivosidenib
K
L
- labetalol
- lamotrigine
- lapatinib
- lasmiditan
- lefamulin
- lemborexant
- lenvatinib
- leuprolide
- levalbuterol
- levamlodipine
- levetiracetam
- levocetirizine
- levodopa
- levofloxacin
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levorphanol
- lidocaine
- linagliptin
- lindane topical
- linezolid
- liraglutide
- lisdexamfetamine
- lisinopril
- lixisenatide
- lofexidine
- lomefloxacin
- loperamide
- lorazepam
- lorcaserin
- losartan
- loxapine
- lumateperone
- lurasidone
- lvp solution with hypertonic saline
M
- macimorelin
- magnesium salicylate
- maprotiline
- mavorixafor
- mazindol
- meclizine
- meclofenamate
- mefenamic acid
- mefloquine
- melatonin
- meloxicam
- meperidine
- mephenytoin
- mephobarbital
- meprobamate
- mesalamine
- mesoridazine
- metaproterenol
- metaxalone
- metformin
- methadone
- methamphetamine
- methdilazine
- methocarbamol
- methohexital
- methotrimeprazine
- methoxamine
- methoxyflurane
- methsuximide
- methyclothiazide
- methyldopa
- methylene blue
- metoclopramide
- metocurine
- metolazone
- metoprolol
- metrizamide
- metronidazole
- metronidazole topical
- metyrosine
- mibefradil
- midazolam
- midostaurin
- mifepristone
- miglitol
- milnacipran
- minocycline
- minoxidil
- mirtazapine
- mitotane
- mivacurium
- mobocertinib
- moexipril
- molindone
- monomethyl fumarate
- morphine
- morphine liposomal
- moxifloxacin
N
- nabilone
- nabumetone
- nadolol
- nalbuphine
- naproxen
- naratriptan
- nateglinide
- nebivolol
- nefazodone
- nicardipine
- nifedipine
- nilutamide
- nimodipine
- nisoldipine
- nitroglycerin
- nitroprusside
- norepinephrine
- norfloxacin
- nortriptyline
O
- ofloxacin
- olanzapine
- oliceridine
- olmesartan
- olodaterol
- olopatadine nasal
- olsalazine
- omadacycline
- ondansetron
- opicapone
- opium
- orphenadrine
- osilodrostat
- osimertinib
- oxaliplatin
- oxaprozin
- oxazepam
- oxcarbazepine
- oxtriphylline
- oxycodone
- oxymorphone
- oxytetracycline
- oxytocin
- ozanimod
P
- pacritinib
- paliperidone
- palonosetron
- pamidronate
- pancuronium
- panobinostat
- papaverine
- paraldehyde
- paramethadione
- paroxetine
- pasireotide
- pazopanib
- pegfilgrastim
- pemetrexed
- pentamidine
- pentazocine
- pentobarbital
- perampanel
- perflutren
- pergolide
- perindopril
- perphenazine
- phenacemide
- phenelzine
- phenindamine
- phenobarbital
- phenoxybenzamine
- phensuximide
- phentermine
- phentolamine
- phenylbutazone
- phenylephrine
- phenytoin
- pimavanserin
- pimozide
- pindolol
- pioglitazone
- pipecuronium
- pirbuterol
- piroxicam
- pitolisant
- polyethylene glycol 3350 with electrolytes
- polythiazide
- ponesimod
- posaconazole
- potassium citrate
- potassium iodide
- pralsetinib
- pramipexole
- pramlintide
- prazosin
- pregabalin
- primaquine
- primidone
- probucol
- procainamide
- procarbazine
- prochlorperazine
- promazine
- promethazine
- propafenone
- propiomazine
- propofol
- propoxyphene
- propranolol
- protriptyline
- psyllium
- pyrilamine
Q
R
- ramelteon
- ramipril
- ranolazine
- rapacuronium
- rasagiline
- relugolix
- remdesivir
- remifentanil
- remimazolam
- repaglinide
- reserpine
- respiratory syncytial virus immune globulin
- rho (d) immune globulin
- ribociclib
- rilpivirine
- risperidone
- ritodrine
- rivastigmine
- rizatriptan
- rocuronium
- rofecoxib
- romidepsin
- ropinirole
- rosiglitazone
- rotigotine
- rucaparib
- rufinamide
S
- safinamide
- salmeterol
- salsalate
- saquinavir
- sarecycline
- sargramostim
- saxagliptin
- scopolamine
- secobarbital
- selegiline
- selpercatinib
- semaglutide
- sertraline
- sevoflurane
- sibutramine
- silodosin
- siponimod
- sirolimus
- sitagliptin
- sodium acetate
- sodium bicarbonate
- sodium chloride
- sodium citrate
- sodium iodide
- sodium iodide i-123
- sodium iodide-i-131
- sodium lactate
- sodium oxybate
- sodium phenylbutyrate
- sodium polystyrene sulfonate
- sodium salicylate
- sodium thiosalicylate
- solifenacin
- sorafenib
- sotagliflozin
- sotalol
- sparfloxacin
- sparsentan
- spironolactone
- st. john's wort
- stiripentol
- succinylcholine
- sufentanil
- sulfamethoxazole
- sulfasalazine
- sulindac
- sumatriptan
- sunitinib
- suvorexant
T
- tacrine
- tacrolimus
- tamoxifen
- tamsulosin
- tapentadol
- tasimelteon
- tbo-filgrastim
- tebentafusp
- telavancin
- telbivudine
- telithromycin
- telmisartan
- temazepam
- temsirolimus
- tenofovir alafenamide
- tenofovir disoproxil
- terazosin
- terbutaline
- terfenadine
- tetrabenazine
- tetracycline
- thalidomide
- theophylline
- thiethylperazine
- thioridazine
- thiothixene
- tiagabine
- tigecycline
- timolol
- tinidazole
- tirzepatide
- tizanidine
- tolazamide
- tolbutamide
- tolcapone
- tolmetin
- topiramate
- toremifene
- torsemide
- tramadol
- trandolapril
- tranylcypromine
- trazodone
- triamterene
- triazolam
- trichlormethiazide
- triclabendazole
- trifluoperazine
- triflupromazine
- trimeprazine
- trimethadione
- trimethaphan camsylate
- trimethobenzamide
- trimipramine
- tripelennamine
- triprolidine
- triptorelin
- troglitazone
- tromethamine
- tryptophan
- tubocurarine
U
V
- valbenazine
- valdecoxib
- valerian
- valproic acid
- valsartan
- vandetanib
- vardenafil
- vasopressin
- vecuronium
- vemurafenib
- venlafaxine
- verapamil
- vigabatrin
- vilazodone
- voclosporin
- voriconazole
- vortioxetine
Z
- zaleplon
- ziconotide
- zidovudine
- ziprasidone
- zoledronic acid
- zolmitriptan
- zolpidem
- zonisamide
- zuranolone
Lithium alcohol/food interactions
There is 1 alcohol/food interaction with lithium.
Lithium disease interactions
There are 12 disease interactions with lithium which include:
- dementia
- cardiac disease
- dehydration
- diarrhea/hyperhidrosis
- hypothyroidism
- renal dysfunction
- sodium depletion
- previous neuroleptic malignant syndrome (NMS)
- seizure disorders
- fever
- hyperprolactinemia/breast cancer
- neutropenia
More about lithium
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Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.