Sominex Maximum Strength Caplet Interactions
There are 450 drugs known to interact with Sominex Maximum Strength Caplet (diphenhydramine), along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 14 are major, 434 are moderate, and 2 are minor.
- View all 450 medications that may interact with Sominex Maximum Strength Caplet
- View Sominex Maximum Strength Caplet alcohol/food interactions (1)
- View Sominex Maximum Strength Caplet disease interactions (8)
Most frequently checked interactions
View interaction reports for Sominex Maximum Strength Caplet (diphenhydramine) and the medicines listed below.
- Aceta w / Codeine (acetaminophen / codeine)
- acetaminophen
- acetaminophen / hydrocodone
- acetaminophen / oxycodone
- Advair HFA (fluticasone / salmeterol)
- Advil (ibuprofen)
- Advil Film-Coated (ibuprofen)
- Advil Migraine (ibuprofen)
- Advil PM (diphenhydramine / ibuprofen)
- Afrin NoDrip Extra Moisturizing (oxymetazoline nasal)
- Aimovig (erenumab)
- Ajovy (fremanezumab)
- Aleve (naproxen)
- alprazolam
- Ambien (zolpidem)
- amlodipine
- Antivert (meclizine)
- Asmanex Twisthaler (mometasone)
- Aspercreme Maximum Strength Lidocaine Creme (lidocaine topical)
- Astelin (azelastine nasal)
- atenolol
- azelastine nasal
- benzocaine topical
- bifidobacterium infantis / lactobacillus acidophilus
- bismuth subsalicylate
- Botox (onabotulinumtoxinA)
- Flexeril (cyclobenzaprine)
- ibuprofen
- OxyContin (oxycodone)
- trazodone
Sominex Maximum Strength Caplet alcohol/food interactions
There is 1 alcohol/food interaction with Sominex Maximum Strength Caplet (diphenhydramine).
Sominex Maximum Strength Caplet disease interactions
There are 8 disease interactions with Sominex Maximum Strength Caplet (diphenhydramine) which include:
- depression
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
Report options
More about Sominex Maximum Strength Caplet (diphenhydramine)
- Compare alternatives
- Drug images
- Latest FDA alerts (2)
- Side effects
- Dosage information
- During pregnancy
- Drug class: anticholinergic antiemetics
- Breastfeeding
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
