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Drug Interactions between diatrizoate and digitoxin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

digitoxin diatrizoate

Applies to: digitoxin and diatrizoate

MONITOR: Addition of an inotropic agent to ionic radiocontrast media may produce a paradoxical depressant response that can be deleterious to the ischemic myocardium. The exact mechanism of interaction is unknown, although ionic radiocontrast agents are known to have a direct depressant effect on cardiac muscles.

MANAGEMENT: Clinicians should be aware of this potential interaction when an inotropic agent is used in combination with ionic radiocontrast media. Patients should be monitored closely for adverse cardiac effects.

References (1)
  1. (2007) "Product Information. Hypaque (diatrizoate)." Amersham Health

Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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