COVID-19 mRNA (Moderna) vaccine Interactions
There are 345 drugs known to interact with COVID-19 mRNA (Moderna) vaccine. Of the total drug interactions, 1 is major, 341 are moderate, and 3 are minor.
- View all 345 medications that may interact with COVID-19 mRNA (Moderna) vaccine
Most frequently checked interactions
View interaction reports for COVID-19 mRNA (Moderna) vaccine and the medicines listed below.
- Advil (ibuprofen)
- Aleve (naproxen)
- Aspirin Low Strength (aspirin)
- Ativan (lorazepam)
- Benadryl (diphenhydramine)
- Boostrix (Tdap) (diphtheria toxoid / pertussis, acellular / tetanus toxoid)
- CoQ10 (ubiquinone)
- Eliquis (apixaban)
- EPA Fish Oil (omega-3 polyunsaturated fatty acids)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Fluzone (influenza virus vaccine, inactivated)
- Fluzone High-Dose (influenza virus vaccine, inactivated)
- Iron Sulfate (ferrous sulfate)
- Lexapro (escitalopram)
- Lipitor (atorvastatin)
- Metoprolol Succinate ER (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Mucinex (guaifenesin)
- Paxlovid (nirmatrelvir / ritonavir)
- PreserVision AREDS 2 (multivitamin with minerals)
- Prilosec (omeprazole)
- Shingrix (zoster vaccine, recombinant)
- Tylenol (acetaminophen)
- Tylenol Extra Strength (acetaminophen)
- Tylenol with Codeine #3 (acetaminophen / codeine)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Zinc (zinc sulfate)
- Zyrtec (cetirizine)
Report options
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More about COVID-19 mRNA (Moderna) vaccine
- COVID-19 mRNA (Moderna) vaccine consumer information
- Compare alternatives
- Reviews (32)
- Latest FDA alerts (1)
- Side effects
- Dosage information
- During pregnancy
- Drug class: viral vaccines
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.