Covid-19 Mrna (Moderna) Vaccine Dosage

Medically reviewed by Drugs.com. Last updated on Sep 6, 2024.

Usual Adult Dose for COVID-19

White labeled single dose vial OR prefilled syringe (50 mcg/0.5 mL): 0.5 mL IM once, administered at least 2 months after the last dose of vaccine

Comments:

• The US FDA issued a Biologics License Application (BLA) to allow the emergency use of this unapproved product for active immunization to prevent COVID-19. This product is not approved by the US FDA for this use.
• There are no data available regarding interchangeability of COVID-19 vaccine products; the same vaccine product should be used for both doses.
• For additional information: https://www.fda.gov/emergency-preparedness-and-response/mcm-legal-regulatory-and-policy-framework/emergency-use-authorization

Use: Active immunization to prevent COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Usual Pediatric Dose for COVID-19

12 years and older:

• White labeled single dose vial OR prefilled syringe (50 mcg/0.5 mL): 0.5 mL IM once, administered at least 2 months after the last dose of vaccine

Comments:

• This drug is not approved by the US FDA to prevent COVID-19. The US FDA has issued a BLA for the use of this drug to prevent COVID-19.
• For additional information: https://www.fda.gov/emergency-preparedness-and-response/mcm-legal-regulatory-and-policy-framework/emergency-use-authorization

Use: Active immunization to prevent COVID-19 caused by SARS-CoV-2

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Patients with a known history of severe allergic reaction to the active component or any of the ingredients
• Patients with a severe allergic reaction (e.g., anaphylaxis) following administration of a COVID-19 vaccine

Safety and efficacy have not been established in patients younger than 12 years; this drug is not recommended for use in these patients.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Administer IM.

Storage requirements:

• Store frozen between -50C to -15C (-58F to 5F); store in original package to protect from sun and ultraviolet light.
• Thaw before use; once thawed, do not return to freezer.
• Thawed vials and syringes may be handled in room light conditions.
• After thawing, this vaccine may be stored between 8C and 25C (46F to 77F) for up to of 12 hours; additionally, prefilled syringes and vials may be stored in the refrigerator between 2C to 8C (36F to 46F) for up to 60 days (or up to the expiration date on the carton, whichever comes first).
• Do not refreeze.

Reconstitution/preparation techniques:

• Do not dilute.
• Consult the Fact Sheet for Health Care Providers.

General:

• This information pertains only to the vaccine product supplied in a vial with a white label stating "COVID-19 Vaccine, mRNA, Spikevax 2024-2025 Formula, For 12 years and older".
• This vaccine may contain white or translucent particulates.

Patient advice:

• To report suspected adverse reactions, contact the Vaccine Adverse Event Reporting System (VAERS): https://vaers.hhs.gov

Frequently asked questions

• COVID-19 vaccines and variants: What you should know

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer