Sinemet Interactions
There are 489 drugs known to interact with Sinemet (carbidopa/levodopa), along with 12 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 46 are major, 432 are moderate, and 11 are minor.
- View all 489 medications that may interact with Sinemet
- View Sinemet alcohol/food interactions (1)
- View Sinemet disease interactions (12)
Most frequently checked interactions
View interaction reports for Sinemet (carbidopa / levodopa) and the medicines listed below.
- amantadine
- amlodipine
- aspirin
- Aspirin Low Strength (aspirin)
- atorvastatin
- Azilect (rasagiline)
- clonazepam
- gabapentin
- Lasix (furosemide)
- levothyroxine
- Lexapro (escitalopram)
- Lipitor (atorvastatin)
- lisinopril
- melatonin
- metformin
- metoprolol
- MiraLAX (polyethylene glycol 3350)
- Mirapex (pramipexole)
- omeprazole
- pantoprazole
- Plavix (clopidogrel)
- ropinirole
- simvastatin
- Synthroid (levothyroxine)
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Zoloft (sertraline)
Sinemet alcohol/food interactions
There is 1 alcohol/food interaction with Sinemet (carbidopa / levodopa).
Sinemet disease interactions
There are 12 disease interactions with Sinemet (carbidopa / levodopa) which include:
- glaucoma
- cardiac disease
- hypotension
- neuroleptic malignant syndrome
- psychoses/depression
- psychosis
- glaucoma
- liver/renal
- melanoma
- reactive airway disease
- depression
- GI bleeding
Report options
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More about Sinemet (carbidopa / levodopa)
- Sinemet consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (30)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Drug class: dopaminergic antiparkinsonism agents
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
