Sinemet Alternatives Compared
| Sinemet | Ropinirole | Pramipexole |
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| Sinemet (carbidopa / levodopa) | Ropinirole | Pramipexole |
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Prescription only
Sinemet is a medication that may be used for the treatment of Parkinson's disease that is available in three different strengths: Sinemet 25/100, Sinemet 25/250, and Sinemet 10/100. Dyskinesias... View more |
Prescription only
Ropinirole is used in the treatment of restless legs syndrome and Parkinson's disease; however, it may cause drowsiness which has caused some people to fall asleep while driving - do not drive if... View more |
Prescription only
Pramipexole is a dopamine agonist (mimics the effects of the neurotransmitter dopamine) that may be used in the treatment of Parkinson's disease and Restless Legs Syndrome. It may cause spontaneous... View more |
Related suggestions Restless Legs Syndrome
Parkinson's Disease
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| More about Sinemet (carbidopa / levodopa) | More about Ropinirole | More about Pramipexole | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Sinemet has an average rating of 7.8 out of 10 from a total of 30 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 11% reported a negative effect. |
Ropinirole has an average rating of 6.5 out of 10 from a total of 328 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 26% reported a negative effect. |
Pramipexole has an average rating of 6.7 out of 10 from a total of 238 ratings on Drugs.com. 57% of reviewers reported a positive effect, while 26% reported a negative effect. |
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| Side Effects | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Sinemet prices |
View all Ropinirole prices |
View all Pramipexole prices |
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| Dosage Forms Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other carbidopa / levodopa brands include: Atamet, Crexont, Dhivy, Duopa, Parcopa, Rytary |
N/A |
Mirapex ER | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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2.3 hours |
6 hours |
8.9 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 489 drugs are known to interact with Sinemet:
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A total of 305 drugs are known to interact with Ropinirole:
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A total of 258 drugs are known to interact with Pramipexole:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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May 02, 1975 |
September 19, 1997 |
July 01, 1997 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.