Drug Interactions between amitriptyline and Jemperli
This report displays the potential drug interactions for the following 2 drugs:
- amitriptyline
- Jemperli (dostarlimab)
Interactions between your drugs
No interactions were found between amitriptyline and Jemperli. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
amitriptyline
A total of 713 drugs are known to interact with amitriptyline.
- Amitriptyline is in the drug class tricyclic antidepressants.
-
Amitriptyline is used to treat the following conditions:
- Anxiety and Stress (off-label)
- Burning Mouth Syndrome (off-label)
- Chronic Myofascial Pain (off-label)
- Chronic Pain
- Cough (off-label)
- Cyclic Vomiting Syndrome (off-label)
- Depression
- Depressive Psychosis (off-label)
- Dysautonomia (off-label)
- Fibromyalgia (off-label)
- Headache
- Hyperhidrosis (off-label)
- Insomnia (off-label)
- Interstitial Cystitis (off-label)
- Irritable Bowel Syndrome (off-label)
- Migraine
- Migraine Prevention (off-label)
- Neuropathic Pain (off-label)
- Neurotic Depression (off-label)
- Pain (off-label)
- Persistent Depressive Disorder (off-label)
- Post Traumatic Stress Disorder (off-label)
- Pudendal Neuralgia (off-label)
- Reflex Sympathetic Dystrophy Syndrome (off-label)
- Somatoform Pain Disorder (off-label)
- Urinary Incontinence (off-label)
- Vulvodynia (off-label)
Jemperli
A total of 557 drugs are known to interact with Jemperli.
- Jemperli is in the drug class anti-PD-1 and PD-L1 monoclonal antibodies (immune checkpoint inhibitors).
- Jemperli is used to treat the following conditions:
Drug and food interactions
amitriptyline food
Applies to: amitriptyline
GENERALLY AVOID: Concomitant use of ethanol and a tricyclic antidepressant (TCA) may result altered TCA plasma levels and efficacy, and additive impairment of motor skills, especially driving skills. Acute ethanol ingestion may inhibit TCA metabolism, while chronic ingestion of large amounts of ethanol may induce hepatic TCA metabolism.
MANAGEMENT: Patients should be advised to avoid alcohol during TCA therapy. Alcoholics who have undergone detoxification should be monitored for decreased TCA efficacy. Dosage adjustments may be required.
References (7)
- Dorian P, Sellers EM, Reed KL, et al. (1983) "Amitriptyline and ethanol: pharmacokinetic and pharmacodynamic interaction." Eur J Clin Pharmacol, 25, p. 325-31
- Warrington SJ, Ankier SI, Turner P (1986) "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology, 15, p. 31-7
- Sandoz M, Vandel S, Vandel B, Bonin B, Allers G, Volmat R (1983) "Biotransformation of amitriptyline in alcoholic depressive patients." Eur J Clin Pharmacol, 24, p. 615-21
- Ciraulo DA, Barnhill JG, Jaffe JH (1988) "Clinical pharmacokinetics of imipramine and desipramine in alcoholics and normal volunteers." Clin Pharmacol Ther, 43, p. 509-18
- Seppala T, Linnoila M, Elonen E, Mattila MJ, Makl M (1975) "Effect of tricyclic antidepressants and alcohol on psychomotor skills related to driving." Clin Pharmacol Ther, 17, p. 515-22
- Ciraulo DA, Barnhill JG, Jaffe JH, Ciraulo AM, Tarmey MF (1990) "Intravenous pharmacokinetics of 2-hydroxyimipramine in alcoholics and normal controls." J Stud Alcohol, 51, p. 366-72
- Ciraulo DA, Alderson LM, Chapron DJ, Jaffe JH, Subbarao B, Kramer PA (1982) "Imipramine disposition in alcoholics." J Clin Psychopharmacol, 2, p. 2-7
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.