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Topical antihistamines

What are Topical antihistamines?

Topical antihistamines are products that have been manufactured for use on the skin, in the nose, or in the eye. They contain antihistamines which are medicines that block histamine release from histamine-1 receptors and are used to treat the symptoms of an allergic reaction such as edema (swelling), itch, inflammation (redness), sneezing, or a runny nose or watery eyes.

Nasal and ocular topical antihistamines may be used in the treatment of allergic rhinitis (hay fever). Topical antihistamine creams may be used to relieve pain and itching due to insect bites, minor cuts and burns, and to resolve rashes due to an allergy or plants such as poison ivy, poison oak, or poison sumac. Some topical antihistamines may also be used in the treatment of atopic dermatitis or lichen simplex chronicus.

List of Topical antihistamines

View by  Generic | Brand
Drug Name Avg. Rating Reviews
Benadryl Extra Strength Itch Stopping Gel (Pro)
Generic name: diphenhydramine
8.0
1 review
Zonalon (Pro)
Generic name: doxepin
No reviews
Prudoxin (Pro)
Generic name: doxepin
No reviews
Itch Relief
Generic name: diphenhydramine
No reviews
Benadryl Original Strength Itch Stopping Cream
Generic name: diphenhydramine/zinc acetate
No reviews
Benadryl Extra Strength Spray
Generic name: diphenhydramine/zinc acetate
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See also

Medical conditions treated or associated with topical antihistamines:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.