Rezdiffra Dosage

Recommended Dosage and Administration

The recommended dosage of REZDIFFRA is based on actual body weight. For patients weighing:

• <100 kg, the recommended dosage is 80 mg orally once daily.
• ≥100 kg, the recommended dosage is 100 mg orally once daily.

Administer REZDIFFRA with or without food.

Dosage Modifications for CYP2C8 Inhibitors

Concomitant use of REZDIFFRA with strong CYP2C8 inhibitors (e.g., gemfibrozil) is not recommended.

If REZDIFFRA is used concomitantly with a moderate CYP2C8 inhibitor (e.g., clopidogrel), reduce the dosage of REZDIFFRA:

• <100 kg, reduce the dosage of REZDIFFRA to 60 mg once daily.
• ≥100 kg, reduce the dosage of REZDIFFRA to 80 mg once daily.