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Propylthiouracil Dosage

Medically reviewed by Drugs.com. Last updated on Jun 3, 2024.

Applies to the following strengths: 50 mg

Usual Adult Dose for Hyperthyroidism

Initial dose: 100 mg orally every 8 hours
Maintenance dose: 100 to 150 mg orally daily administered in 3 equally divided doses approximately every 8 hours

Comments:


Uses:

Usual Adult Dose for Thyroid Storm

Initial dose: 100 mg orally every 8 hours
Maintenance dose: 100 to 150 mg orally daily administered in 3 equally divided doses approximately every 8 hours

Comments:


Uses:

Usual Pediatric Dose for Hyperthyroidism

6 years or older:
Initial dose: 50 mg orally daily in 3 equally divided doses approximately every 8 hours


OR,
6 to 10 years of age:
Initial dose: 50 to 150 mg orally daily in 3 equally divided doses approximately every 8 hours
10 years or older:
Initial dose: 150 to 300 mg orally daily in 3 equally divided doses approximately every 8 hours

Maintenance dose: 50 mg orally twice a day when euthyroid

Comments:

Use: For the treatment of hyperthyroidism in pediatric patients when, in rare instances other therapies are not an option.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

Elderly: Dose selection should be cautious, reflecting the greater frequency of decreased hepatic, renal, cardiac function, and concomitant disease or other drug therapy.

Precautions

US BOXED WARNINGS:


Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Missed dose: If a dose is missed, take it as soon as you remember; if it is almost time for your next dose, skip the missed dose. Do not double your dose.

General:

Monitoring:

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.