Mresvia Dosage

Generic name: RNA-100-AR02 50ug in 0.5mL
Dosage form: injection

Medically reviewed by Drugs.com. Last updated on May 31, 2024.

Administer a single dose (0.5 mL) of MRESVIA as an intramuscular injection.

MRESVIA is supplied as a pre-filled syringe that contains a frozen suspension that must be thawed prior to administration.

Thaw each syringe before use, either in the refrigerator or at room temperature, following the instructions in Table 1.

Table 1: Thawing Conditions and Times
Configuration	Thaw in Refrigerator	Thaw at Room Temperature
Carton of one pre-filled syringe in single blister pack	Thaw between 2°C to 8°C (36°F to 46°F) for 60 minutes. Let each pre‑filled syringe stand at room temperature for between 10 and 20 minutes before administering the vaccine.	Thaw between 15°C to 25°C (59°F to 77°F) for 45 minutes. If MRESVIA is thawed at room temperature, the vaccine is ready to be administered.
Carton of 10 pre-filled syringes in blister packs	Thaw between 2°C to 8°C (36°F to 46°F) for 155 minutes. Let each pre‑filled syringe stand at room temperature for between 10 and 20 minutes before administering the vaccine.	Thaw between 15°C to 25°C (59°F to 77°F) for 140 minutes. If MRESVIA is thawed at room temperature, the vaccine is ready to be administered.

•: After thawing, do not refreeze.
•: Do not shake. Syringes should not be returned to the refrigerator after standing at room temperature.
•: Pre-filled syringes may be stored at 8°C to 25°C (46°F to 77°F) for a total of 24 hours after removal from refrigerated conditions. Discard the thawed pre-filled syringe if not used within this time.
•: Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
•: MRESVIA is a white to off-white suspension that may contain visible white or translucent product-related particulates. Do not administer if the vaccine is discolored or contains other particulate matter.