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Loncastuximab tesirine Disease Interactions

There are 2 disease interactions with loncastuximab tesirine.

Moderate

Loncastuximab tesirine (applies to loncastuximab tesirine) hepatic impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease

Patients with mild hepatic impairment should be monitored for a potential increase of adverse effects when using loncastuximab tesirine. This drug has not been studied in patients with moderate or severe hepatic impairment.

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Moderate

Loncastuximab tesirine (applies to loncastuximab tesirine) kidney disease

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction

The effects of severe renal impairment and end-stage renal disease in the pharmacokinetics of loncastuximab tesirine is unknown.

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Loncastuximab tesirine drug interactions

There are 520 drug interactions with loncastuximab tesirine.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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