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SMOFlipid Disease Interactions

There are 2 disease interactions with SMOFlipid (fat emulsion).

Major

Fat emulsion (applies to SMOFlipid) hypertriglyceridemia

Major Potential Hazard, Moderate plausibility. Applicable conditions: Hyperlipidemia, Diabetes Mellitus, Obesity

Parenteral nutrition fat emulsion products are contraindicated in patients with severe lipid metabolism disorders characterized by hypertriglyceridemia (serum triglycerides greater than 1000 mg/dL). Patients with conditions such as inherited lipid disorders, diabetes mellitus, obesity, or metabolic syndromes are at increased risk while in treatment and should be monitored closely.

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Moderate

Fat emulsion (applies to SMOFlipid) renal impairment

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction

Parenteral nutrition fat emulsion products may cause aluminum toxicity and patients with renal impairment, including preterm neonates, are at increased risk. Caution and monitoring are advised.

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SMOFlipid drug interactions

There is 1 drug interaction with SMOFlipid (fat emulsion).

SMOFlipid alcohol/food interactions

There are 2 alcohol/food interactions with SMOFlipid (fat emulsion).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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