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Dupilumab Disease Interactions

There are 3 disease interactions with dupilumab.

Moderate

Dupilumab (applies to dupilumab) arthralgia

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Psoriatic Arthropathy, Rheumatoid Arthritis

Arthralgia has been reported with the use of dupilumab. Patients should be advised to report new onset or worsening joint symptoms to their health care provider.

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Moderate

Dupilumab (applies to dupilumab) helminth infections

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral

It is unknown if dupilumab with affect the immune response against helminth infections. Patients with preexisting helminth infections should be treated prior to therapy with dupilumab. If patients become infected while receiving dupilumab and do not respond to anthelminthic treatment, dupilumab should be discontinued until the infection resolves.

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Moderate

Dupilumab (applies to dupilumab) visual defects

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Visual Defect/Disturbance

Conjunctivitis and keratitis adverse reactions have been reported with dupilumab. Care should be exercised when using this agent in patients with visual defects. Patients or their caregivers should be advised to report new onset or worsening eye symptoms to their health care provider.

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Dupilumab drug interactions

There are 89 drug interactions with dupilumab.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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