Comparing Xyrem vs Xywav
| Xyrem (sodium oxybate) | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) |
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| Xyrem (sodium oxybate) | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) |
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Prescription only
Xyrem is a Schedule III controlled substance when prescribed to treat narcolepsy; however, there is a high risk of abuse associated with it and people who misuse it or sell it to other people are... View more |
Prescription only
Xywav may be used to treat idiopathic hypersomnia in adults or narcolepsy in adults and children aged 7 and older. It contains 92% less sodium than sodium oxybate (Xyrem) because it is made up of a... View more |
Related suggestions Idiopathic Hypersomnia
Popular comparisons
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| More about Xyrem (sodium oxybate) | More about Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Xyrem has an average rating of 7.6 out of 10 from a total of 108 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 15% reported a negative effect. |
Xywav has an average rating of 8.1 out of 10 from a total of 16 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 13% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Xyrem side effects |
View all Xywav side effects |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Xyrem prices |
View all Xywav prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other sodium oxybate brands include: Lumryz |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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1 hour |
0.66 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 346 drugs are known to interact with Xyrem:
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A total of 346 drugs are known to interact with Xywav:
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| First Approval Date | |||||||||||||||||
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July 17, 2002 |
July 21, 2020 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.