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Xultophy Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Xultophy Ozempic Mounjaro
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Xultophy (insulin degludec / liraglutide) Ozempic (semaglutide) Mounjaro (tirzepatide)
Prescription only

Prescribed for Diabetes - Type 2. Xultophy may also be used for purposes not listed in this medication guide.

Prescription only

Ozempic lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It is... View more

Prescription only

Prescribed for Weight Loss (Obesity/Overweight), Diabetes - Type 2. Mounjaro may also be used for purposes not listed in this medication guide.

Related suggestions
More about Xultophy (insulin degludec / liraglutide) More about Ozempic (semaglutide) More about Mounjaro (tirzepatide)
Ratings & Reviews

Xultophy has an average rating of 9.3 out of 10 from a total of 3 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect.

Ozempic has an average rating of 6.6 out of 10 from a total of 1358 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 25% reported a negative effect.

Mounjaro has an average rating of 8.6 out of 10 from a total of 1060 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 6% reported a negative effect.

View all 3 reviews

View all 1358 reviews

View all 1060 reviews

Drug Class
Side Effects

Xultophy side effects

Ozempic side effects

Mounjaro side effects
Generic Availability

N/A

No lower cost generic approved

No lower cost generic approved
Pricing and Coupons * Prices are without insurance
Quantity 15 mL
Dosage 100 units-3.6 mg/mL
Per Unit* $91.59
Cost* $1,373.87

View all Xultophy prices

Quantity 1.5 mL
Dosage 2 mg/1.5 mL (0.25 mg or 0.5 mg dose)
Per Unit* $686.23
Cost* $1,029.35

View all Ozempic prices

Quantity 2 mL
Dosage 2.5 mg/0.5 mL
Per Unit* $567.62
Cost* $1,135.24

View all Mounjaro prices

Get free Discount Card

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Dosage Forms Available
  • Subcutaneous solution
  • Subcutaneous solution
  • Subcutaneous solution
Brand Names

N/A

 Other semaglutide brands include: Rybelsus, Wegovy Other tirzepatide brands include: Zepbound
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

25 hours

168 hours

120 hours
CSA Schedule ** View glossary of terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category

Summary unavailable.

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.
Drug Interactions

A total of 418 drugs are known to interact with Xultophy:

  • 29 major drug interactions (70 brand and generic names)
  • 364 moderate drug interactions (1929 brand and generic names)
  • 25 minor drug interactions (542 brand and generic names)

A total of 266 drugs are known to interact with Ozempic:

  • 15 major drug interactions (34 brand and generic names)
  • 250 moderate drug interactions (1429 brand and generic names)
  • 1 minor drug interactions (10 brand and generic names)

A total of 411 drugs are known to interact with Mounjaro:

  • 15 major drug interactions (34 brand and generic names)
  • 395 moderate drug interactions (2259 brand and generic names)
  • 1 minor drug interactions (10 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Liraglutide may affect the absorption of other medications that you take by mouth. In some cases... View more
  • Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more
  • Semaglutide may affect the absorption of other medications that you take by mouth. In some cases... View more
  • Talk to your doctor before using alcohol together with semaglutide. Alcohol may affect blood... View more
  • Tirzepatide may affect the absorption of other medications that you take by mouth. In some cases... View more
  • Talk to your doctor before using alcohol together with tirzepatide. Alcohol may affect blood... View more
Disease Interactions
First Approval Date

N/A

N/A

N/A
WADA Class View World Anti-Doping Agency classifications.

N/A

N/A

N/A
More Information
Patient resources
Professional Resources
Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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