Comparing Sudafed 12-Hour vs Zyrtec-D
| Sudafed 12-Hour (pseudoephedrine) | Zyrtec-D (cetirizine / pseudoephedrine) |
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| Sudafed 12-Hour (pseudoephedrine) | Zyrtec-D (cetirizine / pseudoephedrine) |
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Prescription and OTC
Prescribed for Nasal Congestion. Sudafed 12-Hour may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Prescribed for Allergic Rhinitis, Allergies. Zyrtec-D may also be used for purposes not listed in this medication guide. |
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| More about Sudafed 12-Hour (pseudoephedrine) | More about Zyrtec-D (cetirizine / pseudoephedrine) | ||||||||
| Ratings & Reviews | |||||||||
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Sudafed 12-Hour has an average rating of 5.8 out of 10 from a total of 6 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 33% reported a negative effect. |
Zyrtec-D has an average rating of 9.3 out of 10 from a total of 6 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
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View all Sudafed 12-Hour side effects |
View all Zyrtec-D side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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N/A |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Zyrtec-D prices |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Other pseudoephedrine brands include: 12 Hour Decongestant, 12 Hour Nasal Decongestant, Afrinol, Allermed, Cenafed, Children's Dimetapp Decongestant Infant, Chlor-Trimeton Nasal Decongestant, Contac Cold, Decofed, Decofed Liquid, Drixoral Decongestant Non-Drowsy, Efidac, Elixsure Decongestant, Entex, Genaphed, nasofed, Nexafed Nasal Decongestant, Novafed, Silfedrine, Sudafed 24-Hour, Sudafed Congestion, SudoGest, SudoGest 12 Hour, Suphedrin, Suphedrine, Zephrex-D View more | Other cetirizine / pseudoephedrine brands include: 12 Hour Allergy-D, All Day Allergy-D, Allergy D-12, Allergy Relief D, Cetiri D, KS Aller-Tec D-12, Up and Up All Day Allergy Relief D, Zyrtec-D 12 Hour | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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16 hours |
16 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 220 drugs are known to interact with Sudafed 12-Hour:
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A total of 435 drugs are known to interact with Zyrtec-D:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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October 31, 1991 |
N/A |
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| WADA Class View classifications | |||||||||
| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.