Simponi Alternatives Compared
Simponi | Otezla | Upadacitinib |
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Simponi (golimumab) | Otezla (apremilast) | Upadacitinib |
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Prescription only
Prescribed for Ankylosing Spondylitis, Psoriatic Arthritis, Rheumatoid Arthritis, Spondyloarthritis, Ulcerative Colitis. Simponi may also be used for purposes not listed in this medication guide. |
Prescription only
Otezla is a PDE4 inhibitor that may be used to treat adults with plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet’s Disease. It may also be used to treat plaque psoriasis... View more |
Prescription only
Prescribed for Crohn's Disease, Ankylosing Spondylitis, Atopic Dermatitis, Non-Radiographic Axial Spondyloarthritis, Polyarticular Juvenile Idiopathic Arthritis, Psoriatic Arthritis, Rheumatoid... View more |
Related suggestions Popular comparisons
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More about Simponi (golimumab) | More about Otezla (apremilast) | More about Upadacitinib | ||||||||||||||||
Ratings & Reviews | ||||||||||||||||||
Simponi has an average rating of 6.2 out of 10 from a total of 116 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 30% reported a negative effect. |
Otezla has an average rating of 5.1 out of 10 from a total of 435 ratings on Drugs.com. 35% of reviewers reported a positive effect, while 41% reported a negative effect. |
Upadacitinib has an average rating of 6.7 out of 10 from a total of 187 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 22% reported a negative effect. |
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Drug Class | ||||||||||||||||||
Side Effects | ||||||||||||||||||
See also: Simponi side effects in more detail. |
See also: Otezla side effects in more detail. |
See also: upadacitinib side effects in more detail. |
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Generic Availability | ||||||||||||||||||
N/A |
N/A |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
View all Simponi prices |
View all Otezla prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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Dosage Forms Available | ||||||||||||||||||
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N/A |
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Brand Names | ||||||||||||||||||
Other golimumab brands include: Simponi Aria |
N/A |
Rinvoq, Rinvoq LQ | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
336 hours |
9 hours |
14 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||
A total of 483 drugs are known to interact with Simponi:
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A total of 87 drugs are known to interact with Otezla:
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A total of 581 drugs are known to interact with upadacitinib:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||
First Approval Date | ||||||||||||||||||
April 24, 2009 |
March 21, 2014 |
August 16, 2019 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||
Patient resources | ||||||||||||||||||
Professional Resources | ||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.