Comparing Rybelsus vs Xigduo XR
Rybelsus | Xigduo XR |
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Rybelsus (semaglutide) | Xigduo XR (dapagliflozin / metformin) |
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Prescription only
Rybelsus (semaglutide) is an oral medicine that can be used as a first-line medication to improve blood sugar control in adults over the age of 18 with type 2 diabetes. It works by mimicking the... View more |
Prescription only
Prescribed for Heart Failure, Diabetes - Type 2. Xigduo XR may also be used for purposes not listed in this medication guide. |
Related suggestions Diabetes, Type 2
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More about Rybelsus (semaglutide) | More about Xigduo XR (dapagliflozin / metformin) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Rybelsus has an average rating of 6.2 out of 10 from a total of 245 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 27% reported a negative effect. |
Xigduo XR has an average rating of 6.9 out of 10 from a total of 17 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 31% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Rybelsus side effects in more detail. |
See also: Xigduo XR side effects in more detail. |
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Generic Availability | |||||||||||||||||
Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Rybelsus prices |
View all Xigduo XR prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Other semaglutide brands include: Ozempic, Wegovy |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
168 hours |
12.9 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 264 drugs are known to interact with Rybelsus:
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A total of 461 drugs are known to interact with Xigduo XR:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
September 20, 2019 |
October 29, 2014 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.