Ritalin-SR Alternatives Compared
Ritalin-SR | Xyrem | Provigil |
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Ritalin-SR (methylphenidate) | Xyrem (sodium oxybate) | Provigil (modafinil) |
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Prescription only
Prescribed for ADHD, Narcolepsy. Ritalin-SR may also be used for purposes not listed in this medication guide. |
Prescription only
Xyrem is a Schedule III controlled substance when prescribed to treat narcolepsy; however, there is a high risk of abuse associated with it and people who misuse it or sell it to other people are... View more |
Prescription only
Prescribed for Obstructive Sleep Apnea/Hypopnea Syndrome, Shift Work Sleep Disorder, Narcolepsy. Provigil may also be used for purposes not listed in this medication guide. |
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More about Ritalin-SR (methylphenidate) | More about Xyrem (sodium oxybate) | More about Provigil (modafinil) | ||||||||||||||||
Ratings & Reviews | ||||||||||||||||||
Ritalin-SR has an average rating of 7.8 out of 10 from a total of 6 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 20% reported a negative effect. |
Xyrem has an average rating of 7.7 out of 10 from a total of 107 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 14% reported a negative effect. |
Provigil has an average rating of 7.5 out of 10 from a total of 166 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 16% reported a negative effect. |
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Drug Class | ||||||||||||||||||
Side Effects | ||||||||||||||||||
See also: Ritalin-SR side effects in more detail. |
See also: Xyrem side effects in more detail. |
See also: Provigil side effects in more detail. |
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Generic Availability | ||||||||||||||||||
Lower cost generic approved | ||||||||||||||||||
Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Xyrem prices |
View all Provigil prices |
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Dosage Forms Available | ||||||||||||||||||
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Brand Names | ||||||||||||||||||
Other methylphenidate brands include: Adhansia XR, Aptensio XR, Concerta, Cotempla XR-ODT, Daytrana, Jornay PM, Metadate CD, Methylin, Methylin ER, QuilliChew ER, Quillivant XR, Relexxii, Ritalin, Ritalin LA View more | Other sodium oxybate brands include: Lumryz |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
4 hours |
1 hour |
15 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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Pregnancy Category | ||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||
A total of 198 drugs are known to interact with Ritalin-SR:
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A total of 343 drugs are known to interact with Xyrem:
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A total of 506 drugs are known to interact with Provigil:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | ||||||||||||||||||
First Approval Date | ||||||||||||||||||
March 30, 1982 |
July 17, 2002 |
December 24, 1998 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
N/A |
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More Information | ||||||||||||||||||
Patient resources | ||||||||||||||||||
Professional Resources | ||||||||||||||||||
N/A |
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Related Treatment Guide | ||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.