Comparing Paxil CR vs Zoloft
| Paxil CR (paroxetine) | Zoloft (sertraline) |
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| Paxil CR (paroxetine) | Zoloft (sertraline) |
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Prescription only
Prescribed for Dysautonomia, Anxiety, Generalized Anxiety Disorder, Depression, Major Depressive Disorder, Panic Disorder, Postmenopausal Symptoms, Postpartum Depression, Premenstrual Dysphoric... View more |
Prescription only
Zoloft is a brand name for sertraline which is an effective antidepressant with less potential for drowsiness than many other antidepressants. It belongs to the group of medicines called selective... View more |
Related suggestions Depression
Major Depressive Disorder
Panic Disorder
Social Anxiety Disorder
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| More about Paxil CR (paroxetine) | More about Zoloft (sertraline) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Paxil CR has an average rating of 7.6 out of 10 from a total of 57 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 16% reported a negative effect. |
Zoloft has an average rating of 7.3 out of 10 from a total of 1972 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Paxil CR side effects |
View all Zoloft side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Paxil CR prices |
View all Zoloft prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other paroxetine brands include: Brisdelle, Paxil |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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21 hours |
66 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
Excluding Brisdelle
Category X
Not for use in pregnancy
Brisdelle See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 509 drugs are known to interact with Paxil CR:
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A total of 673 drugs are known to interact with Zoloft:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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February 16, 1999 |
December 30, 1991 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.