Comparing Oxybutynin vs Trospium

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Oxybutynin	Trospium	Enter another drug to compare

Oxybutynin

Trospium

Prescription and OTC

Oxybutynin helps to relieve symptoms of an overactive bladder and urinary incontinence but it may cause side effects such as a dry mouth and constipation. Prescribed for Overactive Bladder... View more

Prescription only

Prescribed for Urinary Incontinence, Overactive Bladder, Interstitial Cystitis, Urinary Frequency. Trospium may also be used for purposes not listed in this medication guide.

More about Oxybutynin

More about Trospium

Ratings & Reviews

Oxybutynin has an average rating of 6.7 out of 10 from a total of 459 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 24% reported a negative effect.

Trospium has an average rating of 6.5 out of 10 from a total of 66 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 26% reported a negative effect.

View all 459 reviews

View all 66 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Dry mouth (32.0%)
Constipation (4.8%)
Dizziness (4.8%)
Sweating (4.6%)
Drowsiness (4.1%)
Itching (3.9%)
Nausea (3.7%)

View all Oxybutynin side effects

Constipation (19.7%)
Dry mouth (13.6%)
Difficulty urinating (4.5%)
Tiredness (4.5%)

View all Trospium side effects

Drug Class

Urinary antispasmodics

Urinary antispasmodics

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	100 each
Strength	5 mg
Per unit^*	$0.32
Cost^*	$32.05

View all Oxybutynin prices

Quantity	60 tablet
Strength	20 mg
Per unit^*	$0.50 - $0.51
Cost^*	$30.19 - $30.71

View all Trospium prices

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Dosage Forms

Oral solution
Oral syrup
Oral tablet
Oral tablet, extended release

Oral capsule, extended release
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

2.3 hours

20 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 285 drugs are known to interact with Oxybutynin:

5 major drug interactions (65 brand and generic names)
260 moderate drug interactions (1104 brand and generic names)
20 minor drug interactions (403 brand and generic names)

A total of 316 drugs are known to interact with Trospium:

5 major drug interactions (65 brand and generic names)
295 moderate drug interactions (1385 brand and generic names)
16 minor drug interactions (394 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Ask your doctor before using oxyBUTYnin together with alcohol. Use alcohol cautiously. Alcohol... View more

Trospium should be taken on an empty stomach 1 hour before or 2 hours after a meal unless otherwise... View more
Ask your doctor before using trospium together with alcohol. Use alcohol cautiously. Alcohol may... View more

Disease Interactions

First Approval Date

July 16, 1975

May 28, 2004

WADA Class View classifications

N/A

More Information

Patient Resources

Oxybutynin uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Oxybutynin vs Trospium

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